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Deoxycytidine diphosphate

Deoxycytidine diphosphate is a nucleoside diphosphate. It is related to the common nucleic acid CTP, or cytidine triphosphate, with the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose removed (hence the deoxy- part of the name), and with one fewer phosphoryl group than CTP .

2'-Deoxycytidine diphosphate is abbreviated as dCDP.

Synthesis of cytidine nucleotides

Deoxycytidine diphosphate is synthesized through the oxidation-reduction reaction of cytidine 5'-diphosphocholine which is catalyzed by the presence of ribonucleoside-diphosphate reductase. Additionally, ribonucleoside-diphosphate reductase is capable of binding and catalyzing both the formation of deoxyribonucleotides from ribonucleotide.

References

References

  1. [https://web.archive.org/web/20160307180238/http://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?mode=&index=108353 MeSH term], accessed Dec. 31, 2012
  2. (2020-11-01). "Metabolic drug targets of the cytosine metabolism pathways in the dromedary camel (Camelus dromedarius) and blood parasite Trypanosoma evansi". Tropical Animal Health and Production.
  3. Torrents, Eduard. (2014). "Ribonucleotide reductases: essential enzymes for bacterial life". Frontiers in Cellular and Infection Microbiology.
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nucleotides pyrophosphate-esters pyrimidones
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