Concordance correlation coefficient

Definition

The form of the concordance correlation coefficient \rho_c as{{Cite journal :\rho_c = \frac{2\rho\sigma_x\sigma_y}{\sigma_x^2 + \sigma_y^2 + (\mu_x - \mu_y)^2}, where \mu_x and \mu_y are the means for the two variables and \sigma^2_x and \sigma^2_y are the corresponding variances. \rho is the Pearson's correlation coefficient between the two variables.

This follows from its definition as :\rho_c = 1 - \frac{{\rm Expected\ orthogonal\ squared\ distance\ from\ the\ diagonal\ }x=y} .

When the concordance correlation coefficient is computed on a N-length data set (i.e., N paired data values (x_n, y_n), for n=1,...,N), the form is :\hat{\rho}c = \frac{2 s{xy}}{s_x^2 + s_y^2 + (\bar{x} - \bar{y})^2}, where the mean is computed as :\bar{x} = \frac{1}{N} \sum_{n=1}^N x_n and the variance :s_x^2 = \frac{1}{N} \sum_{n=1}^N (x_n - \bar{x})^2 and the covariance :s_{xy} = \frac{1}{N} \sum_{n=1}^N (x_n - \bar{x})(y_n - \bar{y}) .

Whereas the ordinary correlation coefficient (Pearson's) is immune to whether the biased or unbiased versions for estimation of the variance is used, the concordance correlation coefficient is not. In the original article Lin suggested the 1/N normalization, while in another article Nickerson appears to have used the 1/(N-1),{{Cite journal | author-link = Carol A. E. Nickerson i.e., the concordance correlation coefficient may be computed slightly differently between implementations.

Relation to other measures of correlation

The concordance correlation coefficient is nearly identical to some of the measures called intra-class correlations. Comparisons of the concordance correlation coefficient with an "ordinary" intraclass correlation on different data sets found only small differences between the two correlations, in one case on the third decimal. It has also been stated{{Cite journal | author-link = Klaus Krippendorff | title-link = Sociological Methodology in 1970".

In the original article Lin suggested a form for multiple classes (not just 2). Over ten years later a correction to this form was issued.{{Cite journal | doi-access = free

One example of the use of the concordance correlation coefficient is in a comparison of analysis method for functional magnetic resonance imaging brain scans.

References

For a small Excel and VBA implementation by Peter Urbani see here

References

1. {{Cite Q. Q21012624