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Cilobamine
Chemical compound
Chemical compound
| Field | Value | ||||
|---|---|---|---|---|---|
| IUPAC_name | (2R,3R)-2-(3,4-Dichlorophenyl)-3-[(1-methylethyl)amino]bicyclo[2.2.2]octan-2-ol | ||||
| image | Cilobamine clear.svg | ||||
| image_class | skin-invert-image | ||||
| width | 200 | ||||
| pregnancy_AU | |||||
| pregnancy_US | |||||
| legal_AU | |||||
| legal_CA | |||||
| legal_UK | |||||
| legal_US | |||||
| CAS_number | 69429-84-1 | ||||
| ATC_prefix | none | ||||
| PubChem | 299379 | ||||
| ChemSpiderID | 8557262 | ||||
| ChEMBL | 2106470 | ||||
| UNII_Ref | |||||
| UNII | 067U1T4S30 | ||||
| C | 17 | H=23 | Cl=2 | N=1 | O=1 |
| smiles | Clc1ccc(cc1Cl)[C@@]3(O)C@HC2CCC3CC2 |
Cilobamine is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.
It can clearly be seen that the structure is based on dichloroisoprenaline that has been fused onto the bicycloalkane scaffold.
References
References
- (April 1984). "Dose related induction of the drug metabolizing enzymes of rat liver by cilobamine". Fundamental and Applied Toxicology.
- (1988). "Cilobamine in the treatment of atypical depression". Human Psychopharmacology: Clinical and Experimental.
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