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Carnitine palmitoyltransferase II

Mammalian protein found in humans

Carnitine palmitoyltransferase II

Mammalian protein found in humans

Carnitine O-palmitoyltransferase 2, mitochondrial is an enzyme that in humans is encoded by the CPT2 gene.

Function

Carnitine palmitoyltransferase II precursor (CPT2) is a mitochondrial membrane protein which is transported to the mitochondrial inner membrane. CPT2 together with carnitine palmitoyltransferase I oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders and carnitine palmitoyltransferase II deficiency.

Acyl-CoA from cytosol to the mitochondrial matrix

References

References

  1. (Sep 1992). "Localization of the human gene for carnitine palmitoyltransferase to 1p13-p11 by nonradioactive in situ hybridization". Genomics.
  2. "Entrez Gene: CPT2 carnitine palmitoyltransferase II".
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