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Carboxyl transferase domain
| Field | Value |
|---|---|
| Symbol | Carboxyl_trans |
| Name | Carboxyl_trans |
| image | PDB 1pix EBI.jpg |
| caption | crystal structure of the carboxyltransferase subunit of the bacterial ion pump glutaconyl-coenzyme a decarboxylase |
| Pfam | PF01039 |
| Pfam_clan | CL0127 |
| InterPro | IPR000022 |
| SCOP | 1od2 |
| TCDB | 3.B.1 |
In molecular biology, proteins containing the carboxyl transferase domain include biotin-dependent carboxylases. This domain carries out the following reaction: transcarboxylation from biotin to an acceptor molecule. There are two recognised types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxo acid as the acceptor molecule of carbon dioxide. All of the members in this family use acyl-CoA as the acceptor molecule.
References
References
- (August 1993). "Molecular evolution of biotin-dependent carboxylases". Eur. J. Biochem..
- (September 1993). "Primary structure of the monomer of the 12S subunit of transcarboxylase as deduced from DNA and characterization of the product expressed in Escherichia coli". J. Bacteriol..
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