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Carboxyl transferase domain


FieldValue
SymbolCarboxyl_trans
NameCarboxyl_trans
imagePDB 1pix EBI.jpg
captioncrystal structure of the carboxyltransferase subunit of the bacterial ion pump glutaconyl-coenzyme a decarboxylase
PfamPF01039
Pfam_clanCL0127
InterProIPR000022
SCOP1od2
TCDB3.B.1

In molecular biology, proteins containing the carboxyl transferase domain include biotin-dependent carboxylases. This domain carries out the following reaction: transcarboxylation from biotin to an acceptor molecule. There are two recognised types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxo acid as the acceptor molecule of carbon dioxide. All of the members in this family use acyl-CoA as the acceptor molecule.

References

References

  1. (August 1993). "Molecular evolution of biotin-dependent carboxylases". Eur. J. Biochem..
  2. (September 1993). "Primary structure of the monomer of the 12S subunit of transcarboxylase as deduced from DNA and characterization of the product expressed in Escherichia coli". J. Bacteriol..
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