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Benzamide

Phenyl carboxamide Benzoylamide

| approx. 13 (in H2O) | 23.3 (in DMSO)

| NFPA-H = 1 | NFPA-F = 1 | NFPA-R = 0 | NFPA-S =

Benzamide is an organic compound with the chemical formula of . It is the simplest amide derivative of benzoic acid. In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. It is slightly soluble in water, and soluble in many organic solvents. It is a natural alkaloid found in the herbs of Berberis pruinosa.

Chemical derivatives

A number of substituted benzamides are commercial drugs, including:

; Analgesics

  • Ethenzamide
  • Salicylamide

; Antidepressants

  • Moclobemide ; Antiemetics/Prokinetics
  • Alizapride
  • Batanopride
  • Bromopride
  • Cinitapride
  • Cisapride
  • Clebopride
  • Dazopride
  • Itopride
  • Metoclopramide
  • Mosapride
  • Prucalopride
  • Renzapride
  • Trimethobenzamide
  • Veralipride
  • Zacopride

; Antipsychotics

  • Azapride
  • Amisulpride
  • Levosulpiride
  • Nemonapride
  • Remoxipride
  • Sulpiride
  • Sultopride
  • Tiapride

; Opioids

  • AH-7921
  • Bromadoline
  • U-47700
  • U-77891

; Others

  • 3-Aminobenzamide
  • Alpiropride
  • Aminohippuric acid
  • Chidamide
  • Entinostat
  • Eticlopride
  • Imatinib
  • Mocetinostat
  • Procarbazine
  • Raclopride
  • Sunifiram

References

References

  1. (2014). "Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book)". [[Royal Society of Chemistry.
  2. (2016). "CRC Handbook of Chemistry and Physics". [[CRC Press]].
  3. (October 1991). "Effects of structural changes on acidities and homolytic bond dissociation energies of the hydrogen-nitrogen bonds in amidines, carboxamides, and thiocarboxamides". Journal of the American Chemical Society.
  4. {{PubChem. 2331
  5. "Benzamide {{!}} 55-21-0 supplier and manufacturer".
  6. "benzamide, CAS number 55-21-0".
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benzamides phenyl-compounds
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