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Artemisinic aldehyde Delta11(13)-reductase

Class of enzymes

Field	Value
Name	Artemisinic aldehyde Delta11(13)-reductase
EC_number	1.3.1.92

Artemisinic aldehyde Delta11(13)-reductase (, Dbr2) is an enzyme with systematic name artemisinic aldehyde:NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction

The three substrates of this enzyme are artemisinic aldehyde, reduced nicotinamide adenine dinucleotide phosphate (NADPH), and a proton. Its products are (11R)-dihydroartemisinic aldehyde and oxidised NADP+. This enzyme is present in Artemisia annua.

References

{{KEGG enzyme. 1.3.1.92
(January 2005). "Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua". Planta Medica.
(August 2008). "The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua". The Journal of Biological Chemistry.

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ec-1.3.1

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