From Surf Wiki (app.surf) — the open knowledge base

Arabinosyltransferase

Class of enzymes

Field	Value
Symbol	Arabinose_trans
Name	Arabinosyltransferase
caption	crystal structure of an extracellular domain of arabinofuranosyltransferase from corynebacterium diphtheriae
Pfam	PF04602
Pfam_clan	CL0111
InterPro	IPR007680
CAZy	GT53

An arabinosyltransferase is a transferase enzyme acting upon arabinose. This enzyme is involved in polymerisation of arabinogalactan (an essential component of the mycobacterial cell wall). Mycobacterially, the more precise term is arabinofuranosyltransferase, since the arabinose residues occur only in a furanose form.

This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug ethambutol.

References

(2011). "Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors". ACS Chem. Biol..
(October 1996). "The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol". Proc. Natl. Acad. Sci. U.S.A..

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

protein-families transferases

Want to explore this topic further?

Ask Mako anything about Arabinosyltransferase — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report