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Apolipophorin III

FieldValue
SymbolApoLp-III
NameApoLp-III
imagePDB 1eq1 EBI.jpg
captionnmr structure of an exchangeable apolipoprotein-manduca sexta apolipophorin-iii
PfamPF07464
InterProIPR010009
SCOP1eq1

In molecular biology, the apolipophorin III family of proteins are a family of exchangeable apolipoproteins. Exchangeable apolipoproteins constitute a functionally important family of proteins that play critical roles in lipid transport and lipoprotein metabolism. Apolipophorin III (apoLp-III) is a prototypical exchangeable apolipoprotein found in many insect species that functions in transport of diacylglycerol (DAG) from the fat body lipid storage depot to flight muscles in the adult life stage. The special lipoproteins they form are called lipophorins. High-density lipophorin is characterized by its association with a lower proportion of lipid. It interacts with more lipid and stabilize by Apolipophorin III to form low-density lipophorin. This transformation occurs through tightly regulated and precisely timed processes.

References

References

  1. (February 2002). "Structural basis for the conformational adaptability of apolipophorin III, a helix-bundle exchangeable apolipoprotein". Proc. Natl. Acad. Sci. U.S.A..
  2. Pratheep T, Rameshkumar N, Kayalvizhi N, Suganya T, Karthikeyan S, Krishnan (2017). Changes in lipophorin composition during late larval, pupal and adult stages of Bombyx mori, Acta entomologica sinica, 60(3)- 247-253. doi:10.16380/j.kcxb.2017.03.002. http://www.insect.org.cn/EN/10.16380/j.kcxb.2017.03.002
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