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Annual pharmaceutical drug sales
This is a list of annual sales of patented medications per pharmaceutical group. Because it derives from 10-K data, drugs that have passed loss of exclusivity (LOE) will cease to be on this list.
Annual Sales (2020-present)
| Medication | Trade name | Primary Indication | Company | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|---|
| atorvastatin | Lipitor | Reduction of LDL cholesterol | Pfizer | |||||
| sunitinib malate | Sutent | Advanced and/or metastatic renal cell carcinoma (mRCC) & refractory gastrointestinal stromal tumors (GIST) | Pfizer | |||||
| irinotecan | Camptosar | Metastatic colorectal cancer | Pfizer | |||||
| bimatoprost | Lumigan | Open-angle glaucoma or ocular hypertension | Allergan | |||||
| exemestane | Aromasin | Breast cancer | Pfizer | |||||
| epirubicin | Ellence | Breast cancer | Pfizer | |||||
| trastuzumab | Herceptin | HER2-positive metastatic breast cancer | Genentech | |||||
| gemcitabine | Gemzar | Ovarian cancer, non-small cell lung cancer (NSCLC), metastatic breast cancer (MBC), and pancreatic cancer | Eli Lilly & Co. | |||||
| bevacizumab | Avastin | Metastatic colorectal cancer, non-small cell lung cancer (NSCLC), renal cell carcinoma, HER2-negative breast cancer | Genentech | |||||
| erlotinib | Tarceva | Advanced (metastatic) non-small cell lung cancer (NSCLC) | Genentech | |||||
| brimonidine | Alphagan | Open-angle glaucoma or ocular hypertension | Allergan | |||||
| rituximab | Rituxan | Non-Hodgkin's lymphoma and rheumatoid arthritis | Genentech | |||||
| ranibizumab | Lucentis | Age-related macular degeneration (AMD) | Genentech | |||||
| omalizumab | Xolair | Asthma | Genentech | |||||
| somatropin | Nutropin | Growth hormone deficiency, chronic kidney disease | Genentech | |||||
| dornase alfa | Pulmozyme | Cystic fibrosis (CF) | Genentech | |||||
| efalizumab | Raptiva | Plaque psoriasis | Genentech | |||||
| montelukast | Singulair | Asthma | Merck | |||||
| alendronate sodium | Fosamax | Postmenopausal osteoporosis | Merck | |||||
| sitagliptin | Januvia | Type 2 diabetes | Merck | |||||
| simvastatin | Zocor | Reduction of LDL cholesterol | Merck | |||||
| rizatriptan benzoate | Maxalt | Migraine pain | Merck | |||||
| finasteride | Propecia | Hair loss | Merck | |||||
| etoricoxib | Arcoxia | Osteoarthritis and rheumatoid arthritis | Merck | |||||
| sitagliptin/metformin HCl | Janumet | Type 2 diabetes | Merck | |||||
| finasteride | Proscar | Benign prostatic hyperplasia (enlarged prostate) | Merck | |||||
| aprepitant | Emend | Nausea and vomiting prevention caused by chemotherapy | Merck | |||||
| olanzapine | Zyprexa | Schizophrenia | Eli Lilly & Co. | |||||
| duloxetine HCl | Cymbalta | Depression and generalized anxiety disorder | Eli Lilly & Co. | |||||
| insulin lispro | Humalog | Type 1 diabetes in adults | Eli Lilly & Co. | |||||
| pemetrexed | Alimta | Locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) | Eli Lilly & Co. | |||||
| raloxifene HCl | Evista | Osteoporosis | Eli Lilly & Co. | |||||
| insulin isophane | Humulin | Diabetes | Eli Lilly & Co. | |||||
| teriparatide | Forteo | Osteoporosis | Eli Lilly & Co. | |||||
| atomoxetine HCl | Strattera | Attention-deficit/hyperactivity disorder (ADHD) | Eli Lilly & Co. | |||||
| timolol | Istalol | Open-angle glaucoma | Ista Pharmaceutical | |||||
| bromfenac | Xibrom | Ocular inflammation | Ista Pharmaceutical | |||||
| hyaluronidase | Vitrase | Spreading agent | Ista Pharmaceutica | |||||
| rivaroxaban | Xarelto | Deep vein thrombosis | Johnson & Johnson |
Annual Sales (2010-2020)
| Medication | Trade name | Primary Indication | Company |
|---|---|---|---|
| atorvastatin | Lipitor | Reduction of LDL cholesterol | Pfizer |
| sunitinib malate | Sutent | Advanced and/or metastatic renal cell carcinoma (mRCC) & refractory gastrointestinal stromal tumors (GIST) | Pfizer |
| irinotecan | Camptosar | Metastatic colorectal cancer | Pfizer |
| bimatoprost | Lumigan | Open-angle glaucoma or ocular hypertension | Allergan |
| exemestane | Aromasin | Breast cancer | Pfizer |
| epirubicin | Ellence | Breast cancer | Pfizer |
| trastuzumab | Herceptin | HER2-positive metastatic breast cancer | Genentech |
| gemcitabine | Gemzar | Ovarian cancer, non-small cell lung cancer (NSCLC), metastatic breast cancer (MBC), and pancreatic cancer | Eli Lilly & Co. |
| bevacizumab | Avastin | Metastatic colorectal cancer, non-small cell lung cancer (NSCLC), renal cell carcinoma, HER2-negative breast cancer | Genentech |
| erlotinib | Tarceva | Advanced (metastatic) non-small cell lung cancer (NSCLC) | Genentech |
| brimonidine | Alphagan | Open-angle glaucoma or ocular hypertension | Allergan |
| rituximab | Rituxan | Non-Hodgkin's lymphoma and rheumatoid arthritis | Genentech |
| ranibizumab | Lucentis | Age-related macular degeneration (AMD) | Genentech |
| omalizumab | Xolair | Asthma | Genentech |
| somatropin | Nutropin | Growth hormone deficiency, chronic kidney disease | Genentech |
| dornase alfa | Pulmozyme | Cystic fibrosis (CF) | Genentech |
| efalizumab | Raptiva | Plaque psoriasis | Genentech |
| montelukast | Singulair | Asthma | Merck |
| alendronate sodium | Fosamax | Postmenopausal osteoporosis | Merck |
| sitagliptin | Januvia | Type 2 diabetes | Merck |
| simvastatin | Zocor | Reduction of LDL cholesterol | Merck |
| rizatriptan benzoate | Maxalt | Migraine pain | Merck |
| finasteride | Propecia | Hair loss | Merck |
| etoricoxib | Arcoxia | Osteoarthritis and rheumatoid arthritis | Merck |
| sitagliptin/metformin HCl | Janumet | Type 2 diabetes | Merck |
| finasteride | Proscar | Benign prostatic hyperplasia (enlarged prostate) | Merck |
| aprepitant | Emend | Nausea and vomiting prevention caused by chemotherapy | Merck |
| olanzapine | Zyprexa | Schizophrenia | Eli Lilly & Co. |
| duloxetine HCl | Cymbalta | Depression and generalized anxiety disorder | Eli Lilly & Co. |
| insulin lispro | Humalog | Type 1 diabetes in adults | Eli Lilly & Co. |
| pemetrexed | Alimta | Locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) | Eli Lilly & Co. |
| raloxifene HCl | Evista | Osteoporosis | Eli Lilly & Co. |
| insulin isophane | Humulin | Diabetes | Eli Lilly & Co. |
| teriparatide | Forteo | Osteoporosis | Eli Lilly & Co. |
| atomoxetine HCl | Strattera | Attention-deficit/hyperactivity disorder (ADHD) | Eli Lilly & Co. |
| timolol | Istalol | Open-angle glaucoma | Ista Pharmaceutical |
| bromfenac | Xibrom | Ocular inflammation | Ista Pharmaceutical |
| hyaluronidase | Vitrase | Spreading agent | Ista Pharmaceutica |
| rivaroxaban | Xarelto | Deep vein thrombosis | Johnson & Johnson |
Annual Sales (2000-2010)
| Medication | Trade name | Primary Indication | Company | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| atorvastatin | Lipitor | Reduction of LDL cholesterol | Pfizer | $12,401 | $12,675 | $12,886 | $12,187 | $10,862 | $9,231 | $7,972 | $6,448 | $5,028 | ||||||||
| sunitinib malate | Sutent | Advanced and/or metastatic renal cell carcinoma (mRCC) & refractory gastrointestinal stromal tumors (GIST) | Pfizer | $847 | $581 | $219 | ||||||||||||||
| irinotecan | Camptosar | Metastatic colorectal cancer | Pfizer | $563 | $969 | $903 | $910 | $554 | $299 | |||||||||||
| bimatoprost | Lumigan | Open-angle glaucoma or ocular hypertension | Allergan | $426.2 | $391.7 | $327.5 | $267.6 | $232.9 | $181.3 | $123 | $35.4 | |||||||||
| exemestane | Aromasin | Breast cancer | Pfizer | $465 | $401 | $320 | $247 | $143 | $58 | |||||||||||
| epirubicin | Ellence | Breast cancer | Pfizer | $312 | $367 | $344 | $216 | |||||||||||||
| trastuzumab | Herceptin | HER2-positive metastatic breast cancer | Genentech | $1,382 | $1,287 | $1,234 | $747.2 | $483.2 | $424.8 | $385.2 | $346.7 | $276 | ||||||||
| gemcitabine | Gemzar | Ovarian cancer, non-small cell lung cancer (NSCLC), metastatic breast cancer (MBC), and pancreatic cancer | Eli Lilly & Co. | $1,719.8 | $1,592.4 | $1,408.1 | $1,334.5 | $1,214.4 | $1,021.7 | $875 | $723 | $559.3 | ||||||||
| bevacizumab | Avastin | Metastatic colorectal cancer, non-small cell lung cancer (NSCLC), renal cell carcinoma, HER2-negative breast cancer | Genentech | $2,686 | $2,296 | $1,746 | $1,132 | $554.6 | ||||||||||||
| erlotinib | Tarceva | Advanced (metastatic) non-small cell lung cancer (NSCLC) | Genentech | $457 | $417 | $402 | $274.9 | $13.3 | ||||||||||||
| brimonidine | Alphagan | Open-angle glaucoma or ocular hypertension | Allergan | $286.8 | $248.5 | $250.9 | ||||||||||||||
| rituximab | Rituxan | Non-Hodgkin's lymphoma and rheumatoid arthritis | Genentech | $2,587 | $2,285 | $2,071 | $1,831.4 | $1,574 | $1,360.2 | $1,162.9 | $818.6 | |||||||||
| ranibizumab | Lucentis | Age-related macular degeneration (AMD) | Genentech | $875 | $815 | $380 | ||||||||||||||
| omalizumab | Xolair | Asthma | Genentech | $517 | $472 | $425 | $320.6 | $187.6 | $25.1 | |||||||||||
| somatropin | Nutropin | Growth hormone deficiency, chronic kidney disease | Genentech | $358 | $371 | $378 | $370.5 | $348.8 | $319.5 | |||||||||||
| dornase alfa | Pulmozyme | Cystic fibrosis (CF) | Genentech | $257 | $223 | $199 | $186.5 | $157.1 | $143.7 | $138.1 | $123 | |||||||||
| efalizumab | Raptiva | Plaque psoriasis | Genentech | $108 | $107 | $90 | $79.2 | $52.4 | $1.4 | |||||||||||
| montelukast | Singulair | Asthma | Merck | $4,336.9 | $4,266.3 | $3,579 | $2,975.6 | $2,622 | ||||||||||||
| alendronate sodium | Fosamax | Postmenopausal osteoporosis | Merck | $1,552.7 | $3,049 | $3,134.4 | $3,191.2 | $3,159.7 | ||||||||||||
| sitagliptin | Januvia | Type 2 diabetes | Merck | $1,397.1 | $667.5 | $42.9 | ||||||||||||||
| simvastatin | Zocor | Reduction of LDL cholesterol | Merck | $660.1 | $876.5 | $2,802.7 | $4,381.7 | $5,196.5 | ||||||||||||
| rizatriptan benzoate | Maxalt | Migraine pain | Merck | $529.2 | $467.3 | $406.4 | $348.4 | $309.9 | ||||||||||||
| finasteride | Propecia | Hair loss | Merck | $429.1 | $405.4 | $351.8 | $291.9 | $270.2 | ||||||||||||
| etoricoxib | Arcoxia | Osteoarthritis and rheumatoid arthritis | Merck | $377.3 | $329.1 | $265.4 | $218.2 | |||||||||||||
| sitagliptin/metformin HCl | Janumet | Type 2 diabetes | Merck | $351.1 | $86.4 | |||||||||||||||
| finasteride | Proscar | Benign prostatic hyperplasia (enlarged prostate) | Merck | $323.5 | $411 | $618.5 | $741.4 | $733.1 | ||||||||||||
| aprepitant | Emend | Nausea and vomiting prevention caused by chemotherapy | Merck | $263.8 | $204.2 | $130.8 | $87 | |||||||||||||
| olanzapine | Zyprexa | Schizophrenia | Eli Lilly & Co. | $4,696.1 | $4,761 | $4,363.6 | $4,202.3 | $4,419.8 | $4,276.9 | $3,689 | $3,087 | $2,349.5 | ||||||||
| duloxetine HCl | Cymbalta | Depression and generalized anxiety disorder | Eli Lilly & Co. | $2,697.1 | $2,102.9 | $1,316.4 | $679.7 | $93.9 | ||||||||||||
| insulin lispro | Humalog | Type 1 diabetes in adults | Eli Lilly & Co. | $1,735.8 | $1,474.6 | $1,299.5 | $1,197.7 | $1,101.6 | $1,021.3 | $834 | $628 | $350.2 | ||||||||
| pemetrexed | Alimta | Locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) | Eli Lilly & Co. | $1,154.7 | $854 | $611.8 | $463.2 | $142.6 | ||||||||||||
| raloxifene HCl | Evista | Osteoporosis | Eli Lilly & Co. | $1,075.6 | $1,090.7 | $1,045.3 | $1,036.1 | $1,012.7 | $922.1 | $822 | $665 | $521.5 | ||||||||
| insulin isophane | Humulin | Diabetes | Eli Lilly & Co. | $1,063.2 | $985.2 | $925.3 | $1,004.7 | $997.7 | $1,060.4 | $1,004 | $1,061 | $1,114.5 | ||||||||
| teriparatide | Forteo | Osteoporosis | Eli Lilly & Co. | $778.7 | $709.3 | $594.3 | $389.3 | $238.6 | $65.3 | |||||||||||
| atomoxetine HCl | Strattera | Attention-deficit/hyperactivity disorder (ADHD) | Eli Lilly & Co. | $579.5 | $569.4 | $579 | $552.1 | $666.7 | $370.3 | |||||||||||
| timolol | Istalol | Open-angle glaucoma | Ista Pharmaceutical | $14.6 | $11.3 | $8.3 | $2.6 | |||||||||||||
| bromfenac | Xibrom | Ocular inflammation | Ista Pharmaceutical | $63 | $42.1 | $20.2 | $5.3 | |||||||||||||
| hyaluronidase | Vitrase | Spreading agent | Ista Pharmaceutica | $5.2 | $5.2 | $4.2 | $2.5 | |||||||||||||
| rivaroxaban | Xarelto | Deep vein thrombosis | url=http://www.investor.jnj.com/gov/sec-filings.cfm?DocType=Annual&Year=&SortOrder=Date+Descending&FormatFilter= | title=SEC Filings - Johnson & Johnson | website=www.investor.jnj.com | access-date=2016-03-25 | archive-url=https://web.archive.org/web/20160409090153/http://www.investor.jnj.com/gov/sec-filings.cfm?DocType=Annual&Year=&SortOrder=Date+Descending&FormatFilter= | archive-date=2016-04-09 | url-status=dead}} | $1,868 | $1,522 | $864 | $239 | $25 |
Notes
References
- [https://www.sec.gov/Archives/edgar/data/318771/000031877109000003/form10-k_2008.htm], Genentech 2008 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000119312509040568/dex13.htm], Pfizer 2008 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095015209001897/c49534e10vk.htm], Eli Lilly & Co. 2008 10-K.
- [https://www.sec.gov/Archives/edgar/data/850693/000119312509040955/d10k.htm], Allergan 2008 10-K.
- [https://www.sec.gov/Archives/edgar/data/64978/000095012309003688/y74217e10vk.htm], Merck 2008 10-K.
- [https://www.sec.gov/Archives/edgar/data/930553/000119312509034313/d10k.htm], Ista Pharmaceuticals 2008 10-K.
- [https://www.sec.gov/Archives/edgar/data/318771/000031877108000004/form10-k_2007.htm], Genentech 2007 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000093041308001360/c52104_ex13.htm], Pfizer 2007 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095013708003028/c24001e10vk.htm], Eli Lilly & Co. 2007 10-K.
- [https://www.sec.gov/Archives/edgar/data/850693/000089256908000184/a38161e10vk.htm], Allergan 2007 10-K.
- [https://www.sec.gov/Archives/edgar/data/64978/000095012308002272/y44547e10vk.htm], Merck 2007 10-K.
- [https://www.sec.gov/Archives/edgar/data/930553/000119312508050141/d10k.htm], Ista Pharmaceuticals 2007 10-K.
- [https://www.sec.gov/Archives/edgar/data/318771/000031877107000004/form10-k_2006.htm], Genentech 2006 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000093041307001807/c46660_ex13.htm], Pfizer 2006 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095013707003013/c12621e10vk.htm], Eli Lilly & Co. 2006 10-K.
- [https://www.sec.gov/Archives/edgar/data/850693/000095013707003060/a27376e10vk.htm], Allergan 2006 10-K.
- [https://www.sec.gov/Archives/edgar/data/64978/000095012307002918/y30486e10vk.htm], Merck 2006 10-K.
- [https://www.sec.gov/Archives/edgar/data/930553/000119312506045920/d10k.htm], Ista Pharmaceuticals 2006 10-K.
- [https://www.sec.gov/Archives/edgar/data/318771/000031877106000005/form10-k.htm], Genentech 2005 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000093041306001567/c40966_ex13.htm], Pfizer 2005 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095013706002395/c02657e10vk.htm], Eli Lilly & Co. 2005 10-K.
- [https://www.sec.gov/Archives/edgar/data/850693/000089256906000217/a17071e10vk.htm], Allergan 2005 10-K.
- [https://www.sec.gov/Archives/edgar/data/64978/000095012306003031/y18212e10vk.htm], Merck 2005 10-K.
- [https://www.sec.gov/Archives/edgar/data/318771/000031877105000003/dna-10k_2004.htm], Genentech 2004 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000095012305002379/y06124exv13.htm], Pfizer 2004 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095013405004385/c92539exv13.htm], Eli Lilly & Co. 2004 10-K.
- [https://www.sec.gov/Archives/edgar/data/850693/000095013705002808/a05924e10vk.htm], Allergan 2004 10-K.
- [https://www.sec.gov/Archives/edgar/data/318771/000031877104000002/dna-10k_2003.htm], Genentech 2003 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000095012304003064/y94722exv13.htm], Pfizer 2003 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095013704001857/c83409exv13.htm], Eli Lilly & Co. 2003 10-K.
- [https://www.sec.gov/Archives/edgar/data/850693/000089256904000307/a96815e10vk.htm], Allergan 2003 10-K.
- [https://www.sec.gov/Archives/edgar/data/318771/000031877103000002/dna-10k_2002.htm], Genentech 2002 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000095012303003360/y83976exv13.htm], Pfizer 2002 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095013703001575/c75275exv13.htm], Eli Lilly & Co. 2002 10-K.
- [https://www.sec.gov/Archives/edgar/data/850693/000089256903000654/a87937e10vk.htm], Allergan 2002 10-K.
- [https://www.sec.gov/Archives/edgar/data/78003/000095012302003116/y58494ex13.htm], Pfizer 2001 10-K.
- [https://www.sec.gov/Archives/edgar/data/318771/000031877101500003/form10_k.txt], Genentech 2000 10-K.
- [https://www.sec.gov/Archives/edgar/data/59478/000095013101001634/0000950131-01-001634-0005.txt], Eli Lilly & Co. 2000 10-K.
- "SEC Filings - Johnson & Johnson".
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