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Amlodipine/olmesartan

Combination antihypertensive drug


Combination antihypertensive drug

FieldValue
typecombo
component1Amlodipine
class1Calcium channel blocker
component2Olmesartan
class2Angiotensin II antagonist
tradenameAzor, Sevikar
Drugs.com
DailyMedIDAmlodipine and olmesartan
pregnancy_AUD
pregnancy_AU_comment
routes_of_administrationBy mouth
ATC_prefixC09
ATC_suffixDB02
legal_AUS4
legal_AU_comment
legal_BR
legal_CA
legal_DE
legal_NZ
legal_UKPOM
legal_UK_comment
legal_USRx-only
legal_US_comment
legal_UN
legal_status
CAS_number28981-97-7
KEGGD10285
synonymsOlmesartan/amlodipine

| Drugs.com =

Amlodipine/olmesartan, sold under the brand name Azor, among others is a fixed-dose combination medication used to treat high blood pressure. It contains amlodipine, as the besilate, a dihydropyridine calcium channel blocker, and olmesartan medoxomil, an angiotensin II receptor blocker.

Amlodipine/olmesartan was approved for medical use in the United States in September 2007. It is available as a generic medication.

Medical uses

The combination is indicated for the treatment of hypertension, alone or with other antihypertensive agents, to lower blood pressure.

History

The combination has been studied in clinical trials; one test showed it reduced blood pressure during a 24-hour period and was well tolerated.

References

References

  1. "TGA eBS - Product and Consumer Medicine Information Licence".
  2. "OLAMLO, OLMAKAR, OLMESARTAN/AMLODIPINE ASTRON, OLMESARTAN/AMLODIPINE INTAS (Accord Healthcare Pty Ltd)".
  3. (27 May 2022). "SEVIKAR 20/5 olmesartan medoxomil / amlodipine (as besilate) 20/5 mg tablet blister pack (157565)".
  4. (11 July 2022). "Sevikar 20 mg/5 mg Film-Coated Tablets - Summary of Product Characteristics (SmPC)".
  5. (7 September 2022). "Azor- amlodipine besylate and olmesartan medoxomil tablet, film coated".
  6. (7 June 2022). "Azor- amlodipine besylate and olmesartan medoxomil tablet, film coated".
  7. (May 2025). "Drug Approval Package: Azor (amlodipine and olmesartan medoxomil) NDA #022100".
  8. (June 2009). "American society of hypertension and american urological association". Pharmacy & Therapeutics.
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