Surf Wiki
Save to docs
general/amines

From Surf Wiki (app.surf) — the open knowledge base

Aminopropionitrile

Aminopropionitrile, also known as β-aminopropionitrile (BAPN), is an organic compound with both amine and nitrile functional groups. It is a colourless liquid. The compound occurs naturally and is of interest in the biomedical community.

Biochemical and medical occurrence

BAPN is the toxic constituent of peas from Lathyrus plants, e.g., Lathyrus odoratus. Lathyrism, a disease known for centuries, encompasses 2 distinct entities: a disorder of connective tissue, causing either bone deformity (osteolathyrism) or aortic aneurisms (angiolathyrim). BAPN causes osteolathyrism and angiolathyrism when ingested in large quantities." It can cause osteolathyrism, neurolathyrism, and/or angiolathyrism.

It is an antirheumatic agent in veterinary medicine.

It has attracted interest as an anticancer agent.

Production

Aminopropionitrile is prepared by the reaction of ammonia with acrylonitrile.

References

References

  1. (25 March 2005). "Aminopropionitrile - Compound Summary". National Center for Biotechnology Information.
  2. (2016). "CRC Handbook of Chemistry and Physics". [[CRC Press]].
  3. (2014). "Lathyrus". [[American Association for Clinical Chemistry]].
  4. (2012). "Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection". Blood.
  5. Chvapil, Milos "Inhibition of breast adenocarcinoma growth by intratumoral injection of lipophilic long-acting lathyrogens" Anti-Cancer Drugs 2005, volume 16, 201-210. {{doi. 10.1097/00001813-200502000-00013
  6. Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in ''Ullmann's Encyclopedia of Industrial Chemistry'', Wiley-VCH, Weinheim, 2005. {{doi. 10.1002/14356007.a02_001
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

amines nitriles plant-toxins
Want to explore this topic further?

Ask Mako anything about Aminopropionitrile — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report