Agent Orange

Chemical composition

The active ingredient of Agent Orange was an equal mixture of two phenoxy herbicides – 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) – in iso-octyl ester form, which contained traces of the dioxin 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD was a trace, but significant, contaminant of Agent Orange (typically 2–3 ppm, ranging from 50 ppb to 50 ppm).

Toxicology

TCDD is the most toxic of the dioxins and is classified as a human carcinogen by the U.S. Environmental Protection Agency (EPA). The fat-soluble nature of TCDD causes it to accumulate easily in the food chain, and can enter the body readily through physical contact or ingestion. When TCDD binds to cytoplasmic aryl hydrocarbon receptor (AhR), a transcription factor, the protein translocates to the cell nucleus, where it influences gene expression.

According to U.S. government reports, if not bound chemically to a biological surface such as soil, leaves or grass, Agent Orange dries quickly after spraying and breaks down within hours to days when exposed to sunlight and is no longer harmful.

Development

Several herbicides were developed as part of efforts by the United States and the United Kingdom to create herbicidal weapons for use during World War II. These included 2,4-D, 2,4,5-T, MCPA (2-methyl-4-chlorophenoxyacetic acid, 1414B and 1414A, recoded LN-8 and LN-32), and isopropyl phenylcarbamate (1313, recoded LN-33).

In 1943, the United States Department of the Army contracted botanist (and later bioethicist) Arthur Galston, who discovered the defoliants later used in Agent Orange, and his employer University of Illinois Urbana-Champaign to study the effects of 2,4-D and 2,4,5-T on cereal grains (including rice) and broadleaf crops. While a graduate and post-graduate student at the University of Illinois, Galston's research and dissertation focused on finding a chemical means to make soybeans flower and fruit earlier. He discovered both that 2,3,5-triiodobenzoic acid (TIBA) would speed up the flowering of soybeans and that in higher concentrations it would defoliate the soybeans. From these studies arose the concept of using aerial applications of herbicides to destroy enemy crops to disrupt their food supply. In early 1945, the U.S. Army ran tests of various 2,4-D and 2,4,5-T mixtures at the Bushnell Army Airfield in Florida. As a result, the U.S. began a full-scale production of 2,4-D and 2,4,5-T and would have used it against Japan in 1946 during Operation Downfall if the war had continued.

In the years after the war, the U.S. tested 1,100 compounds, and field trials of the more promising ones were done at British stations in India and Australia, in order to establish their effects in tropical conditions, as well as at the U.S. testing ground in Florida. Between 1950 and 1952, trials were conducted in Tanganyika, at Kikore and Stunyansa, to test arboricides and defoliants under tropical conditions. The chemicals involved were 2,4-D, 2,4,5-T, and endothall (3,6-endoxohexahydrophthalic acid). During 1952–53, the unit supervised the aerial spraying of 2,4,5-T in Kenya to assess the value of defoliants in the eradication of tsetse fly.

Early use

In Malaya, the local unit of Imperial Chemical Industries researched defoliants as weed killers for rubber plantations. Roadside ambushes by the Malayan National Liberation Army were a danger to the British Commonwealth forces during the Malayan Emergency, several trials were made to defoliate vegetation that might hide ambush sites, but hand removal was found cheaper. A detailed account of how the British experimented with the spraying of herbicides was written by two scientists, E. K. Woodford of Agricultural Research Council's Unit of Experimental Agronomy and H. G. H. Kearns of the University of Bristol.

After the Malayan Emergency ended in 1960, the U.S. considered the British precedent in deciding that the use of defoliants was a legal tactic of warfare. Secretary of State Dean Rusk advised President John F. Kennedy that the British had established a precedent for warfare with herbicides in Malaya.

Use in the Vietnam War

In mid-1961, President Ngo Dinh Diem of South Vietnam asked the United States to help defoliate the lush jungle that was providing cover to his enemies. During the Vietnam War, the forests of Vietnam were used for specialised combat "Guerrilla Warfare" were primarily used by the Viet Cong, in which this combat relied on dense foliage and jungle. In August of that year, the Republic of Vietnam Air Force conducted herbicide operations with American help. Diem's request launched a policy debate in the White House and the State and Defense Departments. Many U.S. officials supported herbicide operations, pointing out that the British had already used herbicides and defoliants in Malaya during the 1950s. In November 1961, Kennedy authorized the start of Operation Ranch Hand, the codename for the United States Air Force's herbicide program in Vietnam. The herbicide operations were formally directed by the government of South Vietnam.

During the Vietnam War, between 1962 and 1971, the United States military sprayed nearly 20,000,000 U.S.gal of various chemicals – the "rainbow herbicides" and defoliants – in Vietnam, eastern Laos, and parts of Cambodia as part of Operation Ranch Hand, reaching its peak from 1967 to 1969. For comparison purposes, an olympic size pool holds approximately 660,000 U.S.gal. As the British did in Malaya, the goal of the U.S. was to defoliate rural/forested land, depriving guerrillas of food and concealment and clearing sensitive areas such as around base perimeters and possible ambush sites along roads and canals. Samuel P. Huntington argued that the program was also part of a policy of forced draft urbanization, which aimed to destroy the ability of peasants to support themselves in the countryside, forcing them to flee to the U.S.-dominated cities, depriving the guerrillas of their rural support base.

Agent Orange was usually sprayed from helicopters or from low-flying C-123 Provider aircraft planes, fitted with sprayers and "MC-1 Hourglass" pump systems and 1,000 U.S.gal chemical tanks. Spray runs were also conducted from trucks, boats, and backpack sprayers. Altogether, over 80,000,000 L of Agent Orange were applied.

The first batch of herbicides was unloaded at Tan Son Nhut Air Base in South Vietnam on January 9, 1962. U.S. Air Force records show that at least 6,542 spraying missions took place throughout Operation Ranch Hand. By 1971, 12 percent of the total area of South Vietnam had been sprayed with defoliating chemicals, at an average concentration of 13 times the recommended U.S. Department of Agriculture application rate for domestic use. In South Vietnam alone, an estimated 39,000 sqmi of agricultural land was ultimately destroyed. In some areas, TCDD concentrations in soil and water were hundreds of times greater than the levels considered safe by the EPA.

The campaign destroyed 20,000 sqkm of upland and mangrove forests and thousands of square kilometres of crops. Overall, more than 20% of South Vietnam's forests were sprayed at least once over the nine years. 3.2% of South Vietnam's cultivated land was sprayed at least once between 1965 and 1971. 90% of herbicide use was directed at defoliation.

The U.S. military began targeting food crops in October 1962, primarily using Agent Blue; the American public was not made aware of the crop destruction programs until 1965 (and it was then believed that crop spraying had begun that spring). In 1965, 42% of all herbicide spraying was dedicated to food crops. In 1965, members of the U.S. Congress were told, "crop destruction is understood to be the more important purpose ... but the emphasis is usually given to the jungle defoliation in public mention of the program." The first official acknowledgment of the programs came from the State Department in March 1966.

When crops were destroyed, the Viet Cong would compensate for the loss of food by confiscating more food from local villages. Some military personnel reported being told they were destroying crops used to feed guerrillas, only to later discover, most of the destroyed food was actually produced to support the local civilian population. Wil Verwey wrote in 1977 that ecologist Arthur H. Westing, during a 1969 visit to Quang Ngai province, had been told that 15 crop destruction missions had been approved in the province for 1970. According Verwey, these missions would have been enough to cover 85% of crop lands in the province and would have caused famine and left hundreds of thousands of people without food or malnourished although it was unclear if all the approved missions were actually carried out. According to a report by the American Association for the Advancement of Science, the herbicide campaign had disrupted the food supply of more than 600,000 people by 1970.

Many experts at the time, including plant physiologist and bioethicist Arthur Galston, opposed herbicidal warfare because of concerns about the side effects to humans and the environment from indiscriminately spraying the chemical over a wide area. As early as 1966, resolutions were introduced to the United Nations charging that the U.S. was violating the 1925 Geneva Protocol, which regulated the use of chemical and biological weapons in international conflicts. The U.S. defeated most of the resolutions, arguing that Agent Orange was not a chemical or a biological weapon as it was considered a herbicide and a defoliant and it was used in effort to destroy plant crops and to deprive the enemy of concealment and not meant to target human beings. The U.S. delegation argued that a weapon, by definition, is any device used to injure, defeat, or destroy living beings, structures, or systems, and Agent Orange did not qualify under that definition. It also argued that if the U.S. were to be charged for using Agent Orange, then the United Kingdom and its Commonwealth nations should be charged since they also used it widely during the Malayan Emergency in the 1950s. In 1969, the United Kingdom commented on the draft Resolution 2603 (XXIV):The evidence seems to us to be notably inadequate for the assertion that the use in war of chemical substances specifically toxic to plants is prohibited by international law. The environmental destruction caused by this defoliation has been described by Swedish Prime Minister Olof Palme, lawyers, historians and other academics as an ecocide.

A study carried out by the Bionetic Research Laboratories between 1965 and 1968 found malformations in test animals caused by 2,4,5-T, a component of Agent Orange. The study was later brought to the attention of the White House in October 1969. Other studies reported similar results and the Department of Defense began to reduce the herbicide operation. On April 15, 1970, it was announced that the use of Agent Orange was suspended. Two brigades of the Americal Division in the summer of 1970 continued to use Agent Orange for crop destruction in violation of the suspension. An investigation led to disciplinary action against the brigade and division commanders because they had falsified reports to hide its use. Defoliation and crop destruction were completely stopped by June 30, 1971.

File:Agent-Orange--stack-of-55-gallon-drums.jpg|Stacks of 200 L drums containing Agent Orange. File:'Ranch Hand' run.jpg|Defoliant spray run, part of Operation Ranch Hand, during the Vietnam War by UC-123B Provider aircraft. File:US-Army-APC-spraying-Agent-Orange-in-Vietnam.jpg|U.S. Army armored personnel carrier (APC) spraying Agent Orange over Vietnamese rice fields during the Vietnam War. File:Defoliation agent spraying.jpg|A UH-1D helicopter from the 336th Aviation Company sprays a defoliation agent over farmland in the Mekong Delta. File:VA042083 River Bank Defoliation.jpg|U.S. Army Operations In Vietnam: River bank defoliation File:Agent Orange Cropdusting.jpg|A U.S. Air Force Fairchild C-123 Provider aircraft crop-dusting in Vietnam during Operation Ranch Hand. File:UC-123B Ranch Hand spraying 1962.jpg|A Fairchild C-123 Provider aircraft spraying defoliant in South Vietnam in 1962. File:Ranch Hand UC-123 clearing a roadside in central South Vietnam in 1966.JPG|Ranch Hand UC-123 clearing a roadside in central South Vietnam in 1966. File:110303-F-XN622-007 U.S. Air Force aircraft spraying defoliant.JPG|U.S. Air Force aircraft spraying defoliant File:VA002930 Spraying Agent Orange in Mekong Delta near Can Tho.jpg|Spraying Agent Orange in Mekong Delta near Can Tho, 1969

Health effects

There are various types of cancer associated with Agent Orange, including chronic B-cell leukemia, Hodgkin's lymphoma, multiple myeloma, non-Hodgkin lymphoma, prostate cancer, respiratory cancer, lung cancer, and soft tissue sarcomas. Some literature claims that neither Agent Orange nor its contaminants are carcinogenic in humans.

Vietnamese people

Main article: Impact of Agent Orange in Vietnam

The government of Vietnam states that 4 million of its citizens were exposed to Agent Orange, and as many as 3 million have suffered illnesses because of it; these figures include their children who were exposed. The Red Cross of Vietnam estimates that up to 1 million people are disabled or have health problems due to Agent Orange contamination. The United States government has challenged these figures as being unreliable.

According to a study by Dr. Nguyen Viet Nhan, children in the areas where Agent Orange was used have been affected and have multiple health problems, including cleft palate, mental disabilities, hernias, and extra fingers and toes. In the 1970s, high levels of dioxin were found in the breast milk of South Vietnamese women, and in the blood of U.S. military personnel who had served in Vietnam. The most affected zones are the mountainous area along Truong Son (Long Mountains) and the border between Vietnam and Cambodia. The affected residents are living in substandard conditions with many genetic diseases.

In 2006, Anh Duc Ngo and colleagues of the University of Texas Health Science Center published a meta-analysis that exposed a large amount of heterogeneity (different findings) between studies, a finding consistent with a lack of consensus on the issue. Despite this, statistical analysis of the studies they examined resulted in data that the increase in birth defects/relative risk (RR) from exposure to agent orange/dioxin "appears" to be on the order of 3 in Vietnamese-funded studies, but 1.29 in the rest of the world. There is data near the threshold of statistical significance suggesting Agent Orange contributes to stillbirths, cleft palate, and neural tube defects, with spina bifida being the most statistically significant defect. The large discrepancy in RR between Vietnamese studies and those in the rest of the world has been ascribed to bias in the Vietnamese studies.

Twenty-eight of the former U.S. military bases in Vietnam, where the herbicides were stored and loaded onto airplanes, may still have high levels of dioxins in the soil, posing a health threat to the surrounding communities. Extensive testing for dioxin contamination has been conducted at the former U.S. airbases in Da Nang, Phù Cát District and Biên Hòa. Some of the soil and sediment on the bases have extremely high levels of dioxin, requiring remediation. The Da Nang Air Base has dioxin contamination up to 350 times higher than international recommendations for action. The contaminated soil and sediment continue to affect the citizens of Vietnam, poisoning their food chain and causing illnesses, serious skin diseases and a variety of cancers in the lungs, larynx, and prostate. File:Agent Orange Deformities (3786919757).jpg|A person with birth deformities associated with prenatal exposure to Agent Orange File:Agent-Orange-dioxin-skin-damage-Vietnam.jpg|Major Tự Đức Phang was exposed to dioxin-contaminated Agent Orange. File:A vietnamese Professor is pictured with a group of handicapped children.jpg|A group of handicapped children in Ho Chi Minh, some of them affected by Agent Orange File:Two Vietnameses pose in front of the billboard.jpg|Kan Lay, 55 years old, and her son, Ke Van Bec, 14 years old, A Luoi Valley, Vietnam, December 2004.

U.S and allied veterans

While in Vietnam, U.S. and Free World Military Assistance Forces soldiers were told not to worry about Agent Orange and were persuaded that the chemical was harmless. After returning home, Vietnam veterans from all countries that served began to suspect their ill health or the instances of their wives having miscarriages or children born with birth defects might be related to Agent Orange and the other toxic herbicides to which they had been exposed in Vietnam.

U.S veterans

U.S. Veterans began to file claims in 1977 to the Department of Veterans Affairs for disability payments for health care for conditions they believed were associated with exposure to Agent Orange, or more specifically, dioxin, but their claims were denied unless they could prove the condition began when they were in the service or within one year of their discharge. In order to qualify for compensation, U.S. veterans must have served on or near the perimeters of military bases in Thailand during the Vietnam Era, where herbicides were tested and stored outside of Vietnam, veterans who were crew members on C-123 planes flown after the Vietnam War, or were associated with Department of Defense (DoD) projects to test, dispose of, or store herbicides in the U.S.

By April 1993, the Department of Veterans Affairs had compensated only 486 victims, although it had received disability claims from 39,419 soldiers who had been exposed to Agent Orange while serving in Vietnam.

In a November 2004 Zogby International poll of 987 people, 79% of respondents thought the U.S. chemical companies that produced Agent Orange defoliant should compensate U.S. soldiers who were affected by the toxic chemical used during the war in Vietnam, and 51% said they supported compensation for Vietnamese Agent Orange victims.

Australian and New Zealand veterans

Several official investigations in Australia failed to prove otherwise even though extant American investigations had already established that defoliants were sprayed at U.S. airbases including Bien Hoa Air Base where Australian and New Zealand forces first served before being given their own Tactical area of responsibility (TAOR.) Even then, Australian and New Zealand non-military and military contributions saw personnel from both countries spread over Vietnam such as the hospitals at Bong Son and Qui Nhon, on secondments at various bases, and as flight crew and ground crew for flights into and out of Da Nang Air Base - all areas that were well-documented as having been sprayed.

It wasn't until a group of Australian veterans produced official military records, maps, and mission data as proof that the TAOR controlled by Australian and New Zealand forces in Vietnam had been sprayed with the chemicals in the presence of personnel that the Australian government was forced to change its stance. Only in 1994 did the Australian government finally admit that it was true that defoliants had been used in areas of Vietnam where Australian forces operated, and the effects of these may have been detrimental to some Vietnam veterans and their children.

It was only in 2015 that the official Australian War Memorial accepted rewriting the official history of Australia's involvement in the Vietnam War to acknowledge that Australian soldiers were exposed to defoliants used in Vietnam.

New Zealand was even slower to correct its error, with the government going as far as to deny the legitimacy of the Australian reports in a report called the "McLeod Report," published by Veterans Affairs NZ in 2001, thus infuriating New Zealand veterans and those associated with their cause.

In 2006 progress was made in the form of a Memorandum of Understanding signed between the New Zealand government, representatives of New Zealand Vietnam veterans, and the Royal New Zealand Returned and Services' Association (RSA) for monetary compensation for New Zealand Vietnam veterans who have conditions as evidence of association with exposure to Agent Orange, as determined by the United States National Academy of Sciences. In 2008, the New Zealand government finally admitted that New Zealanders had been exposed to Agent Orange while serving in Vietnam, and the experience was responsible for detrimental health conditions in veterans and their children. Amendments to the memorandum made in 2021 meant that more veterans were eligible for an ex gratia payment of NZ$40,000.

National Academy of Medicine (Institute of Medicine)

Starting in the early 1990s, the federal government directed the Institute of Medicine (IOM), renamed the National Academy of Medicine, to issue reports every 2 years on the health effects of Agent Orange and similar herbicides. First published in 1994 and titled Veterans and Agent Orange, the IOM reports assess the risk of both cancer and non-cancer health effects. Each health effect is categorized by evidence of association based on available research data. The last update was published in 2016, entitled Veterans and Agent Orange: Update 2014.

The report shows sufficient evidence of an association with soft tissue sarcoma; non-Hodgkin lymphoma (NHL); Hodgkin disease; Chronic lymphocytic leukemia (CLL); including hairy cell leukemia and other chronic B-cell leukemias. Limited or suggested evidence of an association was linked with respiratory cancers (lung, bronchus, trachea, larynx); prostate cancer; multiple myeloma; and bladder cancer. Numerous other cancers were determined to have inadequate or insufficient evidence of links to Agent Orange.

The National Academy of Medicine has repeatedly concluded that any evidence suggestive of an association between Agent Orange and prostate cancer is "limited because chance, bias, and confounding could not be ruled out with confidence."

At the request of the Veterans Administration, the Institute of Medicine evaluated whether service in these C-123 aircraft could have plausibly exposed soldiers and been detrimental to their health. Their report Post-Vietnam Dioxin Exposure in Agent Orange-Contaminated C-123 Aircraft confirmed it.

U.S. Public Health Service

Publications by the United States Public Health Service have shown that Vietnam veterans, overall, have increased rates of cancer, and nerve, digestive, skin, and respiratory disorders. The Centers for Disease Control and Prevention notes that in particular, there are higher rates of acute/chronic leukemia, Hodgkin's lymphoma and non-Hodgkin's lymphoma, throat cancer, prostate cancer, lung cancer, colon cancer, Ischemic heart disease, soft tissue sarcoma, and liver cancer. Except liver cancer, these are the same conditions the U.S. Veterans Administration has determined may be associated with exposure to Agent Orange/dioxin and are on the list of conditions eligible for compensation and treatment.

Military personnel who were involved in storage, mixture and transportation (including aircraft mechanics), and actual use of the chemicals were probably among those who received the heaviest exposures. Military members who served on Okinawa also claim to have been exposed to the chemical, but there is no verifiable evidence to corroborate these claims.

Some studies have suggested that veterans exposed to Agent Orange may be more at risk of developing prostate cancer and potentially more than twice as likely to develop higher-grade, more lethal prostate cancers. However, a critical analysis of these studies and 35 others consistently found that there was no significant increase in prostate cancer incidence or mortality in those exposed to Agent Orange or 2,3,7,8-tetracholorodibenzo-p-dioxin.

U.S. Veterans of Laos and Cambodia

During the Vietnam War, the United States fought the North Vietnamese, and their allies, in Laos and Cambodia, including heavy bombing campaigns. They also sprayed large quantities of Agent Orange in each of those countries. According to one estimate, the U.S. dropped 475,500 U.S.gal in Laos and 40,900 U.S.gal in Cambodia. Because Laos and Cambodia were both officially neutral during the Vietnam War, the U.S. attempted to keep secret its military operations in those countries, from the American population and has largely avoided compensating American veterans and CIA personnel stationed in Cambodia and Laos who suffered permanent injuries as a result of exposure to Agent Orange there.

One noteworthy exception, according to the U.S. Department of Labor, is a claim filed with the CIA by an employee of "a self-insured contractor to the CIA that was no longer in business." The CIA advised the Department of Labor that it "had no objections" to paying the claim and Labor accepted the claim for payment:

Ecological impact

About 17.8% or 3100000 ha of the total forested area of Vietnam was sprayed during the war, which disrupted the ecological equilibrium. The persistent nature of dioxins, erosion caused by loss of tree cover, and loss of seedling forest stock meant that reforestation was difficult (or impossible) in many areas. Many defoliated forest areas were quickly invaded by aggressive pioneer species (such as bamboo and cogon grass), making forest regeneration difficult and unlikely. Animal species diversity was also impacted; in one study a Harvard biologist found 24 species of birds and 5 species of mammals in a sprayed forest, while in two adjacent sections of unsprayed forest there were, respectively, 145 and 170 species of birds and 30 and 55 species of mammals.

Dioxins from Agent Orange have persisted in the Vietnamese environment since the war, settling in the soil and sediment and entering the food chain through animals and fish that feed in the contaminated areas. The movement of dioxins through the food web has resulted in bioconcentration and biomagnification. The areas most heavily contaminated with dioxins are former U.S. air bases.

Sociopolitical impact

American policy during the Vietnam War was to destroy crops, accepting the sociopolitical impact that that would have.

Legal and diplomatic proceedings

International

The extensive environmental damage that resulted from usage of the herbicide prompted the United Nations to pass Resolution 31/72 and ratify the Environmental Modification Convention. Many states do not regard this as a complete ban on the use of herbicides and defoliants in warfare, but it does require case-by-case consideration. Article 2(4) of Protocol III of the Convention on Certain Conventional Weapons contains the "Jungle Exception", which prohibits states from attacking forests or jungles "except if such natural elements are used to cover, conceal or camouflage combatants or military objectives or are military objectives themselves".{{cite web |url=https://geneva-s3.unoda.org/static-unoda-site/pages/templates/the-convention-on-certain-conventional-weapons/PROTOCOL%2BIII.pdf |title=Convention on Certain Conventional Weapons, Protocol on Prohibitions or Restrictions on the Use of Incendiary Weapons |publisher=United Nations Office of Disarmament Affairs

Class action lawsuit

Since at least 1978, several lawsuits have been filed against the companies which produced Agent Orange, among them Dow Chemical, Monsanto, and Diamond Shamrock. In 1978, army veteran Paul Reutershan sued Dow Chemical for $10 million, after he was diagnosed with terminal cancer that he believed was a result of Agent Orange exposure. After Reutershan died in December 1978, his attorneys added additional plaintiffs and refiled the lawsuit as a class action. That lawsuit would eventually represent thousands of veterans, and was considered one of the largest and most complex lawsuits ever brought in the US at that time.

Attorney Hy Mayerson was an early pioneer in Agent Orange litigation, working with environmental attorney Victor Yannacone in 1980 on the first class-action suits against wartime manufacturers of Agent Orange. In meeting Dr. Ronald A. Codario, one of the first civilian doctors to see affected patients, Mayerson, so impressed by the fact a physician would show so much interest in a Vietnam veteran, forwarded more than a thousand pages of information on Agent Orange and the effects of dioxin on animals and humans to Codario's office the day after he was first contacted by the doctor. The corporate defendants sought to escape culpability by blaming everything on the U.S. government.

In 1980, Mayerson, with Sgt. Charles E. Hartz, as their principal client, filed the first U.S. Agent Orange class-action lawsuit in Pennsylvania, for the injuries military personnel in Vietnam suffered through exposure to toxic dioxins in the defoliant. Attorney Mayerson co-wrote the brief that certified the Agent Orange Product Liability action as a class action, the largest ever filed as of its filing. Hartz's deposition was one of the first ever taken in America, and the first for an Agent Orange trial, for the purpose of preserving testimony at trial, as it was understood that Hartz would not live to see the trial because of a brain tumor that began to develop while he was a member of Tiger Force, special forces, and LRRPs in Vietnam. The firm also located and supplied critical research to the veterans' lead expert, Dr. Codario, including about 100 articles from toxicology journals dating back more than a decade, as well as data about where herbicides had been sprayed, what the effects of dioxin had been on animals and humans, and every accident in factories where herbicides were produced or dioxin was a contaminant of some chemical reaction.

The chemical companies involved denied that there was a link between Agent Orange and the veterans' medical problems. However, on May 7, 1984, seven chemical companies settled the class-action suit out of court just hours before jury selection was to begin. The companies agreed to pay $180 million as compensation if the veterans dropped all claims against them. Slightly over 45% of the sum was ordered to be paid by Monsanto alone. Many veterans who were victims of Agent Orange exposure were outraged the case had been settled instead of going to court and felt they had been betrayed by the lawyers. "Fairness Hearings" were held in five major American cities, where veterans and their families discussed their reactions to the settlement and condemned the actions of the lawyers and courts, demanding the case be heard before a jury of their peers. Federal Judge Jack B. Weinstein refused the appeals, claiming the settlement was "fair and just". By 1989, the veterans' fears were confirmed when it was decided how the money from the settlement would be paid out. A totally disabled Vietnam veteran would receive a maximum of $12,000 spread out over the course of 10 years. Furthermore, by accepting the settlement payments, disabled veterans would become ineligible for many state benefits that provided far more monetary support than the settlement, such as food stamps, public assistance, and government pensions. A widow of a Vietnam veteran who died of Agent Orange exposure would receive $3,700.

In 2004, Monsanto spokesman Jill Montgomery said Monsanto should not be liable at all for injuries or deaths caused by Agent Orange, saying: "We are sympathetic with people who believe they have been injured and understand their concern to find the cause, but reliable scientific evidence indicates that Agent Orange is not the cause of serious long-term health effects."

On 22 August 2024, the Court of Appeal of Paris dismissed an appeal filed by Tran To Nga against 14 US corporations that supplied Agent Orange for the US army during the war in Vietnam. The lawyers said that Nga will take her case to France's highest appeals court. Only military veterans from the United States and its allies in the war have won compensation so far. Some of the agrochemical companies in the U.S. have compensated U.S. veterans, but not to Vietnamese victims.

New Jersey Agent Orange Commission

In 1980, New Jersey created the New Jersey Agent Orange Commission, the first state commission created to study its effects. The commission's research project in association with Rutgers University was called "The Pointman Project". It was disbanded by Governor Christine Todd Whitman in 1996. During the first phase of the project, commission researchers devised ways to determine trace dioxin levels in blood. Before this, such levels could only be found in the adipose (fat) tissue. The project studied dioxin (TCDD) levels in blood as well as in adipose tissue in a small group of Vietnam veterans who had been exposed to Agent Orange and compared them to those of a matched control group; the levels were found to be higher in the exposed group. The second phase of the project continued to examine and compare dioxin levels in various groups of Vietnam veterans, including Soldiers, Marines, and Brownwater Naval personnel.

U.S. Congress

In 1991, Congress enacted the Agent Orange Act, giving the Department of Veterans Affairs the authority to declare certain conditions "presumptive" to exposure to Agent Orange/dioxin, making these veterans who served in Vietnam eligible to receive treatment and compensation for these conditions. The same law required the National Academy of Sciences to periodically review the science on dioxin and herbicides used in Vietnam to inform the Secretary of Veterans Affairs about the strength of the scientific evidence showing association between exposure to Agent Orange/dioxin and certain conditions. The authority for the National Academy of Sciences reviews and addition of any new diseases to the presumptive list by the VA expired in 2015 under the sunset clause of the Agent Orange Act of 1991. Through this process, the list of 'presumptive' conditions has grown since 1991, and currently the U.S. Department of Veterans Affairs has listed prostate cancer, respiratory cancers, multiple myeloma, type II diabetes mellitus, Hodgkin's disease, non-Hodgkin's lymphoma, soft tissue sarcoma, chloracne, porphyria cutanea tarda, peripheral neuropathy, chronic lymphocytic leukemia, and spina bifida in children of veterans exposed to Agent Orange as conditions associated with exposure to the herbicide. This list now includes B cell leukemias, such as hairy cell leukemia, Parkinson's disease and ischemic heart disease, these last three having been added on August 31, 2010. Several highly placed individuals in government are voicing concerns about whether some of the diseases on the list should, in fact, actually have been included.

In 2011, an appraisal of the 20-year long Air Force Health Study that began in 1982 indicates that the results of the AFHS as they pertain to Agent Orange, do not provide evidence of disease in the Operation Ranch Hand veterans caused by "their elevated levels of exposure to Agent Orange".

The VA initially denied the applications of post-Vietnam C-123 aircrew veterans because, as veterans without "boots on the ground" service in Vietnam, they were not covered under VA's interpretation of "exposed". In June 2015, the Secretary of Veterans Affairs issued an Interim final rule providing presumptive service connection for post-Vietnam C-123 aircrews, maintenance staff and aeromedical evacuation crews. The VA now provides medical care and disability compensation for the recognized list of Agent Orange illnesses.

U.S.–Vietnamese government negotiations

In 2002, Vietnam and the U.S. held a joint conference on Human Health and Environmental Impacts of Agent Orange. Following the conference, the U.S. National Institute of Environmental Health Sciences (NIEHS) began scientific exchanges between the U.S. and Vietnam, and began discussions for a joint research project on the human health impacts of Agent Orange. These negotiations broke down in 2005, when neither side could agree on the research protocol, and the research project was canceled. More progress has been made on the environmental front. In 2005, the first U.S.-Vietnam workshop on remediation of dioxin was held.

Starting in 2005, the EPA began to work with the Vietnamese government to measure the level of dioxin at the Da Nang Air Base. Also in 2005, the Joint Advisory Committee on Agent Orange, made up of representatives of Vietnamese and U.S. government agencies, was established. The committee has been meeting yearly to explore areas of scientific cooperation, technical assistance and environmental remediation of dioxin.

A breakthrough in the diplomatic stalemate on this issue occurred as a result of United States President George W. Bush's state visit to Vietnam in November 2006. In the joint statement, President Bush and President Triet agreed "further joint efforts to address the environmental contamination near former dioxin storage sites would make a valuable contribution to the continued development of their bilateral relationship." On May 25, 2007, President Bush signed the U.S. Troop Readiness, Veterans' Care, Katrina Recovery, and Iraq Accountability Appropriations Act, 2007 into law for the wars in Iraq and Afghanistan that included an earmark of $3 million specifically for funding for programs for the remediation of dioxin 'hotspots' on former U.S. military bases, and for public health programs for the surrounding communities; some authors consider this to be completely inadequate, pointing out that the Da Nang Airbase alone will cost $14 million to clean up, and that three others are estimated to require $60 million for cleanup. The appropriation was renewed in the fiscal year 2009 and again in FY 2010. An additional $12 million was appropriated in the fiscal year 2010 in the Supplemental Appropriations Act and a total of $18.5 million appropriated for fiscal year 2011.

Secretary of State Hillary Clinton stated during a visit to Hanoi in October 2010 that the U.S. government would begin work on the clean-up of dioxin contamination at the Da Nang Airbase. In June 2011, a ceremony was held at Da Nang airport to mark the start of U.S.-funded decontamination of dioxin hotspots in Vietnam. Thirty-two million dollars has so far been allocated by the U.S. Congress to fund the program. A $43 million project began in the summer of 2012, as Vietnam and the U.S. forge closer ties to boost trade and counter China's rising influence in the disputed South China Sea.

Vietnamese victims class action lawsuit in U.S. courts

On January 31, 2004, a victim's rights group, the Vietnam Association for Victims of Agent Orange/dioxin (VAVA), filed a lawsuit in the United States District Court for the Eastern District of New York in Brooklyn, against several U.S. companies for liability in causing personal injury, by developing, and producing the chemical, and claimed that the use of Agent Orange violated the 1907 Hague Convention on Land Warfare, 1925 Geneva Protocol, and the 1949 Geneva Conventions. Dow Chemical and Monsanto were the two largest producers of Agent Orange for the U.S. military and were named in the suit, along with the dozens of other companies (Diamond Shamrock, Uniroyal, Thompson Chemicals, Hercules, etc.). On March 10, 2005, Judge Jack B. Weinstein of the Eastern District – who had presided over the 1984 U.S. veterans class-action lawsuit – dismissed the lawsuit, ruling there was no legal basis for the plaintiffs' claims. He concluded Agent Orange was not considered a poison under international humanitarian law at the time of its use by the U.S.; the U.S. was not prohibited from using it as a herbicide; and the companies that produced the substance were not liable for the method of its use by the government. In the dismissal statement issued by Weinstein, he wrote "The prohibition extended only to gases deployed for their asphyxiating or toxic effects on man, not to herbicides designed to affect plants that may have unintended harmful side-effects on people."

Author and activist George Jackson had written previously that:If the Americans were guilty of war crimes for using Agent Orange in Vietnam, then the British would be also guilty of war crimes as well since they were the first nation to deploy the use of herbicides and defoliants in warfare and used them on a large scale throughout the Malayan Emergency. Not only was there no outcry by other states in response to the United Kingdom's use, but the U.S. viewed it as establishing a precedent for the use of herbicides and defoliants in jungle warfare.The U.S. government was also not a party in the lawsuit because of sovereign immunity, and the court ruled the chemical companies, as contractors of the U.S. government, shared the same immunity. The case was appealed and heard by the Second Circuit Court of Appeals in Manhattan on June 18, 2007. Three judges on the court upheld Weinstein's ruling to dismiss the case. They ruled that, though the herbicides contained a dioxin (a known poison), they were not intended to be used as a poison on humans. Therefore, they were not considered a chemical weapon and thus not a violation of international law. A further review of the case by the entire panel of judges of the Court of Appeals also confirmed this decision. The lawyers for the Vietnamese filed a petition to the U.S. Supreme Court to hear the case. On March 2, 2009, the Supreme Court denied certiorari and declined to reconsider the ruling of the Court of Appeals.

Help for those affected in Vietnam

To assist those who have been affected by Agent Orange/dioxin, the Vietnamese have established "peace villages", which each host between 50 and 100 victims, giving them medical and psychological help. As of 2006, there were 11 such villages, thus granting some social protection to fewer than a thousand victims. U.S. veterans of the war in Vietnam and individuals who are aware and sympathetic to the impacts of Agent Orange have supported these programs in Vietnam. An international group of veterans from the U.S. and its allies during the Vietnam War working with their former enemy—veterans from the Vietnam Veterans Association—established the Vietnam Friendship Village outside of Hanoi.

The center provides medical care, rehabilitation and vocational training for children and veterans from Vietnam who have been affected by Agent Orange. In 1998, The Vietnam Red Cross established the Vietnam Agent Orange Victims Fund to provide direct assistance to families throughout Vietnam that have been affected. In 2004, the Vietnam Association of Victims of Agent Orange (VAVA) was formed. In addition to filing the lawsuit against the chemical companies, VAVA provides medical care, rehabilitation services and financial assistance to those injured by Agent Orange.

The Vietnamese government provides small monthly stipends to more than 200,000 Vietnamese people believed to be affected by the herbicides; this totaled $40.8 million in 2008. The Vietnam Red Cross has raised more than $22 million to assist the ill or disabled, and several U.S. foundations, United Nations agencies, European governments and nongovernmental organizations have given a total of about $23 million for site cleanup, reforestation, health care and other services to those in need.

Vuong Mo of the Vietnam News Agency described one of the centers:

On June 16, 2010, members of the U.S.-Vietnam Dialogue Group on Agent Orange/Dioxin unveiled a comprehensive 10-year Declaration and Plan of Action to address the toxic legacy of Agent Orange and other herbicides in Vietnam. The Plan of Action was released as an Aspen Institute publication and calls upon the U.S. and Vietnamese governments to join with other governments, foundations, businesses, and nonprofits in a partnership to clean up dioxin "hot spots" in Vietnam and to expand humanitarian services for people with disabilities there. On September 16, 2010, Senator Patrick Leahy acknowledged the work of the Dialogue Group by releasing a statement on the floor of the United States Senate. The statement urges the U.S. government to take the Plan of Action's recommendations into account in developing a multi-year plan of activities to address the Agent Orange/dioxin legacy.

Use outside of Vietnam

Australia

In 2008, Australian researcher Jean Williams claimed that cancer rates in Innisfail, Queensland, were 10 times higher than the state average because of secret testing of Agent Orange by the Australian military scientists during the Vietnam War. Williams, who had won the Order of Australia medal for her research on the effects of chemicals on U.S. war veterans, based her allegations on Australian government reports found in the Australian War Memorial's archives. A former soldier, Ted Bosworth, backed up the claims, saying that he had been involved in the secret testing. Neither Williams nor Bosworth has produced verifiable evidence to support their claims. The Queensland health department determined that cancer rates in Innisfail were no higher than those in other parts of the state.

Canada

The U.S. military, with the permission of the Canadian government, tested herbicides, including Agent Orange, in the forests near Canadian Forces Base Gagetown in New Brunswick. In 2007, the government of Canada offered a one-time ex gratia payment of $20,000 as compensation for Agent Orange exposure at CFB Gagetown. On July 12, 2005, Merchant Law Group, on behalf of over 1,100 Canadian veterans and civilians who were living in and around CFB Gagetown, filed a lawsuit to pursue class action litigation concerning Agent Orange and Agent Purple with the Federal Court of Canada. On August 4, 2009, the case was rejected by the court, citing lack of evidence. In 2007, the Canadian government announced that a research and fact-finding program initiated in 2005 had found the base was safe. A legislative commission in the State of Maine found in 2024 that the Canadian investigation was "incorrect, biased, and based upon, in some cases, incomplete data and poor study design—at times exacerbated by the rapid period in which these reports were required to be conducted and issued."

On February 17, 2011, the Toronto Star revealed that Agent Orange had been employed to clear extensive plots of Crown land in Northern Ontario. The Toronto Star reported that, "records from the 1950s, 1960s and 1970s show forestry workers, often students and junior rangers, spent weeks at a time as human markers holding red, helium-filled balloons on fishing lines while low-flying planes sprayed toxic herbicides including an infamous chemical mixture known as Agent Orange on the brush and the boys below." In response to the Toronto Star article, the Ontario provincial government launched a probe into the use of Agent Orange.

Guam

An analysis of chemicals present in the island's soil, together with resolutions passed by Guam's legislature, suggest that Agent Orange was among the herbicides routinely used on and around Andersen Air Force Base and Naval Air Station Agana. Despite the evidence, the Department of Defense continues to deny that Agent Orange was stored or used on Guam. Several Guam veterans have collected evidence to assist in their disability claims for direct exposure to dioxin-containing herbicides, such as 2,4,5-T, which are similar to the illness associations and disability coverage that has become standard for those who were harmed by the same chemical contaminant of Agent Orange used in Vietnam.

South Korea

Agent Orange was used in South Korea in the late 1960s and in 1999, about 20,000 South Koreans filed two separated lawsuits against U.S. companies, seeking more than $5 billion in damages. After losing a decision in 2002, they filed an appeal. In January 2006, the South Korean Appeals Court ordered Dow Chemical and Monsanto to pay $62 million in compensation to about 6,800 people. The ruling acknowledged that "the defendants failed to ensure safety as the defoliants manufactured by the defendants had higher levels of dioxins than standard", and, quoting the U.S. National Academy of Science report, declared that there was a "causal relationship" between Agent Orange and a range of diseases, including several cancers. The judges failed to acknowledge "the relationship between the chemical and peripheral neuropathy, the disease most widespread among Agent Orange victims".

In 2011, the United States local press KPHO-TV in Phoenix, Arizona, alleged that in 1978 that the United States Army had buried 250 55-gallon drums (13,750 U.S.gal) of Agent Orange in Camp Carroll, the U.S. Army base located in Gyeongsangbuk-do, South Korea.

Currently, veterans who provide evidence meeting VA requirements for service in Vietnam and who can medically establish that anytime after this 'presumptive exposure' they developed any medical problems on the list of presumptive diseases, may receive compensation from the VA. Certain veterans who served in South Korea and can prove they were assigned to certain specified areas around the Korean Demilitarized Zone, during a specific time frame, are afforded similar presumption.

New Zealand

The use of Agent Orange has been controversial in New Zealand, because of the exposure of New Zealand troops in Vietnam and because of the production of herbicide used in Agent Orange which has been alleged at various times to have been exported for use in the Vietnam War and to other users by the Ivon Watkins-Dow chemical plant in Paritutu, New Plymouth. What is fact is that from 1962 until 1987, 2,4,5T herbicide was manufactured at the Ivon Watkins-Dow plant for domestic use in New Zealand. It was widely used by farmers and in New Zealand agriculture as a weed killer. This fact was the basis of a 2005 New Zealand Media story that claimed that the herbicide had been allegedly exported to U.S. military bases in South East Asia. However the claim was not proven, a fact which the Media did not subsequently report. There have been continuing claims, as yet unproven, that the suburb of Paritutu has also been polluted. However, the agriscience company Corteva (which split from DowDupont in 2019) agreed to clean up the Paritutu site in September 2022.

Philippines

Herbicide persistence studies of Agents Orange and White were conducted in the Philippines.

Johnston Atoll

The U.S. Air Force operation to remove Herbicide Orange from Vietnam in 1972 was named Operation Pacer IVY, while the operation to destroy the Agent Orange stored at Johnston Atoll in 1977 was named Operation Pacer HO. Operation Pacer IVY collected Agent Orange in South Vietnam and removed it in 1972 aboard the ship MV Transpacific for storage on Johnston Atoll. The EPA reports that 1800000 U.S.gal of Herbicide Orange was stored at Johnston Island in the Pacific and 480000 U.S.gal at Gulfport, Mississippi.

Research and studies were initiated to find a safe method to destroy the materials, and it was discovered that they could be incinerated safely under special conditions of temperature and dwell time. However, these herbicides were expensive, and the Air Force wanted to resell its surplus instead of dumping it at sea. Among many methods tested, a possibility of salvaging the herbicides by reprocessing and filtering out the TCDD contaminant with carbonized (charcoaled) coconut fibers. This concept was then tested in 1976, and a pilot plant constructed at Gulfport.

From July to September 1977, during Operation Pacer HO, the entire stock of Agent Orange from both Herbicide Orange storage sites at Gulfport and Johnston Atoll was subsequently incinerated in four separate burns in the vicinity of Johnston Island aboard the Dutch-owned waste incineration ship . As of 2004, some records of the storage and disposition of Agent Orange at Johnston Atoll have been associated with the historical records of Operation Red Hat.

Okinawa, Japan

There have been dozens of reports in the press about the use and/or storage of military-formulated herbicides on Okinawa that are based upon statements by former U.S. service members that had been stationed on the island, photographs, government records, and unearthed storage barrels. The U.S. Department of Defense has denied these allegations with statements by military officials and spokespersons, as well as a January 2013 report authored by Dr. Alvin Young that was released in April 2013.

In particular, the 2013 report rebuts articles written by journalist Jon Mitchell as well as a statement from "An Ecological Assessment of Johnston Atoll" a 2003 publication produced by the United States Army Chemical Materials Agency that states, "in 1972, the U.S. Air Force also brought about 25,000 200L drums (5,000,000 L) of the chemical, Herbicide Orange (HO) to Johnston Island that originated from Vietnam and was stored on Okinawa." The 2013 report states: "The authors of the [2003] report were not DoD employees, nor were they likely familiar with the issues surrounding Herbicide Orange or its actual history of transport to the Island." and detailed the transport phases and routes of Agent Orange from Vietnam to Johnston Atoll, none of which included Okinawa.

Further official confirmation of restricted (dioxin containing) herbicide storage on Okinawa appeared in a 1971 Fort Detrick report titled "Historical, Logistical, Political and Technical Aspects of the Herbicide/Defoliant Program", which mentions that the environmental statement should consider "Herbicide stockpiles elsewhere in PACOM (Pacific Command) U.S. Government restricted materials Thailand and Okinawa (Kadena AFB)." The 2013 DoD report says that the environmental statement urged by the 1971 report was published in 1974 as "The Department of Air Force Final Environmental Statement", and that the latter did not find Agent Orange was held in either Thailand or Okinawa.

Thailand

Agent Orange was tested by the United States in Thailand during the Vietnam War. In 1999, buried drums were uncovered and confirmed to be Agent Orange. Workers who uncovered the drums fell ill while upgrading the airport near Hua Hin District, 100 km south of Bangkok. Vietnam-era veterans whose service involved duty on or near the perimeters of military bases in Thailand anytime between February 28, 1961, and May 7, 1975, may have been exposed to herbicides and may qualify for VA benefits. A declassified Department of Defense report written in 1973, suggests that there was a significant use of herbicides on the fenced-in perimeters of military bases in Thailand to remove foliage that provided cover for enemy forces. In 2013, the VA determined that herbicides used on the Thailand base perimeters may have been tactical and procured from Vietnam, or a strong, commercial type resembling tactical herbicides.

United States

The University of Hawaiʻi has acknowledged extensive testing of Agent Orange on behalf of the United States Department of Defense in Hawaii along with mixtures of Agent Orange on Hawaii Island in 1966 and on Kaua'i Island in 1967–1968; testing and storage in other U.S. locations has been documented by the United States Department of Veterans Affairs.

In 1971, the C-123 aircraft used for spraying Agent Orange were returned to the United States and assigned various East Coast USAF Reserve squadrons, and then employed in traditional airlift missions between 1972 and 1982. In 1994, testing by the Air Force identified some former spray aircraft as "heavily contaminated" with dioxin residue. Inquiries by aircrew veterans in 2011 brought a decision by the U.S. Department of Veterans Affairs opining that not enough dioxin residue remained to injure these post-Vietnam War veterans. On 26 January 2012, the U.S. Center For Disease Control's Agency for Toxic Substances and Disease Registry challenged this with their finding that former spray aircraft were indeed contaminated and the aircrews exposed to harmful levels of dioxin. In response to veterans' concerns, the VA in February 2014 referred the C-123 issue to the Institute of Medicine for a special study, with results released on January 9, 2015.

In 1978, the EPA suspended spraying of Agent Orange in national forests. Agent Orange was sprayed on thousands of acres of brush in the Tennessee Valley for 15 years before scientists discovered the herbicide was dangerous. Monroe County, Tennessee, is one of the locations known to have been sprayed according to the Tennessee Valley Authority. Forty-four remote acres were sprayed with Agent Orange along power lines throughout the National Forest.

In 1983, New Jersey declared a Passaic River production site to be a state of emergency. The dioxin pollution in the Passaic River dates back to the Vietnam era, when Diamond Alkali manufactured it in a factory along the river. The tidal river carried dioxin upstream and down, contaminating a 17 mi stretch of riverbed in one of New Jersey's most populous areas.

A December 2006 Department of Defense report listed Agent Orange testing, storage, and disposal sites at 32 locations throughout the United States, Canada, Thailand, Puerto Rico, Korea, and in the Pacific Ocean. The Veteran Administration has also acknowledged that Agent Orange was used domestically by U.S. forces in test sites throughout the United States. Eglin Air Force Base in Florida was one of the primary testing sites throughout the 1960s.

Cleanup programs

In February 2012, Monsanto agreed to settle a case covering dioxin contamination around a plant in Nitro, West Virginia, that had manufactured Agent Orange. Monsanto agreed to pay up to $9 million for cleanup of affected homes, $84 million for medical monitoring of people affected, and the community's legal fees.

On 9 August 2012, the United States and Vietnam began a cooperative cleaning up of the toxic chemical on part of Da Nang International Airport, marking the first time the U.S. government has been involved in cleaning up Agent Orange in Vietnam. Danang was the primary storage site of the chemical. Two other cleanup sites the United States and Vietnam are looking at is Biên Hòa, in the southern province of Đồng Nai is a hotspot for dioxin and so is Phù Cát airport in the central province of Bình Định, says U.S. Ambassador to Vietnam David Shear. According to the Vietnamese newspaper Nhân Dân, the U.S. government provided $41 million to the project. As of 2017, some 110,000 m3 of soil have been cleaned.

The Naval Construction Battalion Center at Gulfport, Mississippi was the largest storage site in the United States for Agent Orange. It was about 30 acre in size and was still being cleaned up in 2013.

In 2016, the EPA laid out its plan for cleaning up an 8 mi stretch of the Passaic River in New Jersey, with an estimated cost of $1.4 billion. The contaminants reached to Newark Bay and other waterways, according to the EPA, which has designated the area a Superfund site. Since destruction of the dioxin requires high temperatures over 1,000 C, the destruction process is energy intensive.

Footnotes

References

Citations

General and cited references

• NTP (National Toxicology Program); "Toxicology and Carcinogenesis Studies of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) in Female Harlan Sprague-Dawley Rats (Gavage Studies)", CASRN 1746–01–6, April 2006.
• – both of Young's books were commissioned by the U.S. Department of Defense, Office of the Deputy Under Secretary of Defense (Installations and Environment)

References

1. (January 29, 2014). "Agent Orange Linked To Skin Cancer Risk". Science 2.0.
2. (2010-12-28). "Manufacturing Sites". Agentorangerecord.com.
3. (2022-04-01). "Agent Orange Reviewed: Potential Role in Peripheral Neuropathy and Neurodegeneration". Journal of Military and Veterans' Health.
4. (2011). "TCDD and cancer: A critical review of epidemiologic studies". Taylor and Francis.
5. (1984). "Agent Orange and Birth Defects Risk". Science News.
6. Stocking, Ben. (2007-06-14). "Agent Orange Still Haunts Vietnam, US". The Washington Post.
7. King, Jessica. (2012-08-10). "U.S. in first effort to clean up Agent Orange in Vietnam". [[CNN]].
8. (2025-04-28). "The Vietnam War ended 50 years ago, but the battle with Agent Orange continues".
9. (2011). "Defoliation". ABC-CLIO.
10. Zierler, David. (2011). "The invention of ecocide: agent orange, Vietnam, and the scientists who changed the way we think about the environment". Univ. of Georgia Press.
11. (2022-12-18). "How Imperative Is It To Consider Ecocide As An International Crime?".
12. Falk, Richard A.. (1973). "Environmental Warfare and Ecocide—Facts, Appraisal, and Proposals". Bulletin of Peace Proposals.
13. (2022-02-17). "Industrial disasters from Bhopal to present day: why the proposal to make 'ecocide' an international offence is persuasive – The Leaflet".
14. Giovanni, Chiarini. (2022-04-01). "Ecocide: From the Vietnam War to International Criminal Jurisdiction? Procedural Issues In-Between Environmental Science, Climate Change, and Law".
15. (1976). "Fate of 2,3,7,8-tetrachlorodibenzo-''p''-dioxin (TCDD) in the Environment: Summary and Decontamination Recommendations". United States Air Force Academy.
16. "Dioxins". United States National Library of Medicine.
17. Yonemoto, Junzo. (2000). "The Effects of Dioxin on Reproduction and Development". Industrial Health.
18. Palmer, Michael. (2007). "The Case of Agent Orange". Contemporary Southeast Asia.
19. "Facts About Herbicides – Public Health". United States Department of Veterans Affairs.
20. (April 18, 1985). "This horrible natural experiment". New Scientist.
21. (2008-07-18). "In Memoriam: Arthur Galston, Plant Biologist, Fought Use of Agent Orange".
22. Schneider, Brandon. (2003). "Agent Orange: A deadly member of the rainbow". [[Yale Scientific]].
23. link. (November 21, 2021)
24. Haberman, Clyde. (2014-05-11). "Agent Orange's Long Legacy, for Vietnam and Veterans". The New York Times.
25. Hough, Peter. (1998). "The Global Politics of Pesticides: Forging Consensus from Conflicting Interests". [[Earthscan]].
26. (2016-04-13). "Why Hasn't The Government Learned Anything From The Agent Orange Health Crisis?".
27. (1997). "Agent Orange". ABC-CLIO.
28. Huntington, Samuel P.. (July 1968). "The Bases of Accommodation". Foreign Affairs.
29. (2019-02-11). "Agent Orange and Cancer". American Cancer Society.
30. [https://www.bbc.com/news/world-europe-55795651 Vietnam War: French court to hear landmark Agent Orange case] {{Webarchive. link. (May 3, 2021, ''BBC News'', January 25, 2021)
31. Fawthrop, Tom. (June 14, 2004). "Vietnam's war against Agent Orange". BBC News.
32. Fawthrop, Tom. (February 10, 2008). "Agent of Suffering". The Guardian.
33. Peterson, Doug. (Spring 2005). "Matters of Light: Arthur W. Galston". [[University of Illinois]].
34. Schlager, Neil. (1994). "When Technology Fails: Significant Technological Disasters, Accidents, and Failures of the Twentieth Century". Gale Research.
35. "United States of America: Practice Relating to Rule 76. Herbicides". [[International Committee of the Red Cross]].
36. Lewy, Guenter (1978), ''America in Vietnam'', New York: [[Oxford University Press]], pp. 263
37. (March 24, 2020). "What Is Agent Orange? What Types of Cancer Does It Cause?".
38. (2003). "Dioxin and cancer: a critical review". Regulatory Toxicology and Pharmacology.
39. (December 13, 2010). "Professor Nguyen Viet Nhan: Helping Child Victims of Agent Orange Defoliation".
40. Fox, Diane Niblack. (2024). "Living with Agent Orange: conversations in postwar Viet Nam". University of Massachusetts Press.
41. Thornton, Joe. (2000). "Pandora's Poison: Chlorine, Health, and a New Environmental Strategy". MIT Press.
42. "Ủng hộ nạn nhân chất độc da cam/Đi-ô-xin". Vietnam Ministry of Foreign Affairs.
43. King, Jesse. (2012-11-08). "Birth Defects Caused by Agent Orange". Embryo Project Encyclopedia.
44. Viet Nam – Russia Tropical Centre. (June 2009). "Evaluation of Contamination at the Agent Orange Dioxin Hot Spots in Bien Hoa, Phu Cat and Vicinity, Vietnam". Office of the National Committee 33, Ministry of Natural Resource and Environment.
45. ((Hatfield Consultants Office of the National Steering Committee 33)). (2007). "Assessment of dioxin contamination in the environment and human population in the vicinity of Da Nang Airbase, Viet Nam.". Hatfield Consultants.
46. Denselow, Robin. (December 3, 1998). "Agent Orange blights Vietnam". BBC News.
47. (1994). "History of the Controversy Over the Use of Herbicides". National Academies Press (US).
48. Hermann, Kenneth J.. (April 25, 2006). "Killing Me Softly: How Agent Orange Murders Vietnam's Children". Political Affairs.
49. (November 18, 2014). "Veterans Exposed to Agent Orange: Legislative History, Litigation, and Current Issues". Congressional Research Service.
50. (January 19, 2018). "Veterans Exposed to Agent Orange". United States Department of Veterans Affairs.
51. (2001). "The disability rights movement: from charity to confrontation". Temple University Press.
52. Nguyen, Ha. (November 19, 2004). "Most Americans favor compensation for Agent Orange victims". Embassy of the Socialist Republic of Vietnam in the United States.
53. From the archives: Royal Commission findings clear Agent Orange. https://www.smh.com.au/national/from-the-archives-royal-commission-findings-clear-agent-orange-20190805-p52e0d.html
54. Maps of Heavily Sprayed Areas and Dioxin Hot Spots. https://www.aspeninstitute.org/programs/agent-orange-in-vietnam-program/maps-of-heavily-sprayed-areas-and-dioxin-hot-spots/
55. ' Nurse in Vietnam - Frances Palmer ', URL: https://vietnamwar.govt.nz/memory/nurse-vietnam-frances-palmer, (Ministry for Culture and Heritage), updated 16-Nov-2022
56. "Surgical and medical support". VietnamWar.govt.nz, New Zealand and the Vietnam War.
57. DVA (Department of Veterans' Affairs) (2023 ), Agent Orange and other chemicals in the Vietnam War, DVA Anzac Portal, accessed 24 January 2024, https://anzacportal.dva.gov.au/wars-and-missions/vietnam-war-1962-1975/events/aftermath/agent-orange
58. Pemberton, Gregory. (May 1, 2014). "Win for Vietnam vets with Agent Orange war history to be rewritten".
59. 'Observing Agent Orange ', URL: https://vietnamwar.govt.nz/memory/observing-agent-orange, (Ministry for Culture and Heritage), updated 20-May-2020
60. ' Agent Orange spraying - Ian Thorpe ', URL: https://vietnamwar.govt.nz/audio/agent-orange-spraying-ian-thorpe, (Ministry for Culture and Heritage), updated 10-Sep-2013
61. Māori war veteran's skin still peeling 50 years after Agent Orange exposure
62. 'More Vietnam Veterans to receive compensation for Agent Orange Exposure'. https://www.beehive.govt.nz/release/more-vietnam-veterans-receive-compensation-agent-orange-exposure. (New Zealand Government)
63. "Agent Orange and Cancer Risk {{!}} American Cancer Society".
64. (2018). "Veterans and Agent Orange: Health Effects of Herbicides Used in Vietnam: Update 11". The National Academies Press.
65. ((Committee to Evaluate the Potential Exposure of Agent Orange/TCDD Residue and Level of Risk of Adverse Health Effects for Aircrew of Post-Vietnam C-123 Aircraft; Board on the Health of Select Populations)). "Post-Vietnam Dioxin Exposure in Agent Orange-Contaminated C-123 Aircraft". Institute of Medicine.
66. "Vietnam Era Health Retrospective Observational Study". United States Department of Veterans Affairs.
67. (1987-02-13). "Postservice mortality among Vietnam veterans. The Centers for Disease Control Vietnam Experience Study". JAMA.
68. (March 25, 2010). "Agent Orange: Diseases Associated with Agent Orange Exposure". United States Department of Veterans Affairs.
69. Mitchell, Jon. (April 12, 2011). "Evidence for Agent Orange on Okinawa". [[Japan Times]].
70. (17 October 2008). "Agent Orange exposure, Vietnam War veterans, and the risk of prostate cancer". Cancer.
71. (1 July 2013). "Agent Orange as a risk factor for high-grade prostate cancer". Cancer.
72. (2014). "A critical review of the epidemiology of Agent Orange/TCDD and prostate cancer". Eur J Epidemiol.
73. Dunst, Charles. (20 July 2019). "The U.S.'s Toxic Agent Orange Legacy: Washington Has Admitted to the Long-Lasting Effects of Dioxin Use in Vietnam, But Has Largely Sidestepped the Issue in Neighboring Cambodia and Laos".
74. (August 9, 2012). "4 Decades on, U.S. Starts Cleanup of Agent Orange in Vietnam". The New York Times.
75. [https://www.gao.gov/htext/d05371.html 'Agent Orange: Limited Information Is Available on the Number of Civilians Exposed in Vietnam and Their Workers' Compensation Claims,'] {{Webarchive. link. (February 26, 2021 ''GAO report number GAO-05-371'', April 22, 2005.)
76. Chiras, Daniel D.. (2010). "Environmental science". Jones & Bartlett.
77. Vallero, Daniel A.. (2007). "Biomedical ethics for engineers: ethics and decision making in biomedical and biosystem engineering". Academic Press.
78. Turse, Nick. (2013). "Kill Anything That Moves: The Real American War in Vietnam". Henry Holt and Company.
79. (December 10, 1976). "Convention on the Prohibition of the Military or Any Other Hostile Use of Environmental Modification Techniques". Audiovisual Library of International Law.
80. (2013). "Practice Relating to Rule 76. Herbicides". International Committee of the Red Cross.
81. Detter, Ingrid. (2013). "The Law of War". Ashgate.
82. (2005). "Agent Orange". SAGE Publications.
83. (15 March 1988). "Agent Orange on Trial: Mass Toxic Disasters in the Courts". Belknap Press.
84. (15 February 2014). "Toxic War: The Story of Agent Orange". Vanderbilt University Press.
85. Scott, Wilbur J.. (1993). "The Politics of Readjustment: Vietnam Veterans Since the War". Transaction Publishers.
86. (1980-01-25). "Dying Veteran May Speak From Beyond The Grave In Court". Lakeland Ledger.
87. Croft, Steve. (May 7, 1980). "Agent Orange". CBS Evening News.
88. "About the Firm". The Mayerson Law Offices.
89. (1993). "Challenges in military health care: perspectives on health status and the provision of care". Transaction Publishers.
90. Harrington, John C.. (2005). "The challenge to power: money, investing, and democracy". Chelsea Green Publisher.
91. Wilcox, Fred A.. (1999). "Toxic Agents". Oxford University Press.
92. Fawthrop, Tom. (November 4, 2004). "Agent Orange Victims Sue Monsanto". CorpWatch.
93. (2024-08-22). "French court rejects appeal in Agent Orange lawsuit by French-Vietnamese ex-journalist".
94. (2024-08-22). "French court dismisses appeal in Agent Orange case".
95. (2024-08-22). "Paris court rejects appeal against chemicals giant over Vietnam War use of Agent Orange".
96. (2023-06-17). "The Vietnamese octogenarian fighting for Agent Orange victims".
97. (July 3, 1996). "Agent Orange Panel Closes". The New York Times.
98. (March 18, 1988). "Dioxins and Dibenzofurans in Blood and Adipose Tissue of Agent Orange—Exposed Vietnam Veterans and Matched Controls". JAMA.
99. Pencak, William. (2009). "Encyclopedia of the Veteran in America". ABC-CLIO.
100. Office of Public Health and Environmental Hazards. (2009-11-11). "Agent Orange". United States Department of Veterans Affairs.
101. (1981-11-03). "PL 102-4 and The National Academy of Sciences". The National Academies.
102. "Agent Orange Act of 1991". [[George Washington University]].
103. Baker, Mike. (2010-08-31). "Aging vets' costs concern Obama's deficit co-chair". Boston.com.
104. (2011-09-01). "The Air Force Health Study: An Epidemiologic Retrospective". Annals of Epidemiology.
105. (2015-06-18). "VA Expands Disability Benefits for Air Force Personnel Exposed to Contaminated C-123 Aircraft". United States Department of Veterans Affairs.
106. "US, Vietnam to Hold Fourth Joint Advisory Meeting on Agent Orange/Dioxin". Embassy of the United States, Hanoi.
107. "Joint Statement Between the Socialist Republic of Vietnam and the United States of America". United States Department of State.
108. Leahy, Patrick. "Statement of Senator Patrick Leahy on the Legacy of Agent Orange".
109. DeYoung, Karen. (2010-07-22). "In Hanoi, Clinton highlights closer ties with Vietnam, pushes for human rights". The Washington Post.
110. (2011-06-17). "US helps Vietnam to eradicate deadly Agent Orange". BBC News.
111. Ives, Mike. "US starts landmark Agent Orange cleanup in Vietnam". Yahoo! News.
112. "United Kingdom of Great Britain and Northern Ireland: Practice Relating to Rule 76. Herbicides". International Committee of the Red Cross.
113. (2005-03-10). "Agent Orange Case for Millions of Vietnamese Is Dismissed". The New York Times.
114. {{Cite court. link. (2005)
115. Piette, Adam. (May 25, 2009). "The Literary Cold War, 1945 to Vietnam". [[Edinburgh University Press]].
116. Rusk, Dean. (November 24, 1961). "Foreign Relations of the United States, 1961–1963". United States Department of State.
117. {{cite court. link. (2008)
118. (March 2, 2009). "Docket No. 08-470". Supreme Court of the United States.
119. "Vietnam Friendship Village Project".
120. "Hội Nạn nhân chất độc da cam/dioxin Việt Nam".
121. "50 years of agent orange/dioxin disaster in Vietnam".
122. Ngô Quang Xuân. (June 2009). "Statement to the United States House Foreign Affairs Subcommittee of Asia, Pacific and Global Environment".
123. (2005-12-07). "Living with the sufferings".
124. Grotto, Jason. (2009-12-08). "Public-private group has plan in the works to resolve issue". Chicago Tribune.
125. Mason, Margie. (2010-06-16). "Plan addresses Agent Orange legacy in Vietnam". NBC News.
126. (January–February 2010). "Special Report: Agent Orange".
127. (September 16, 2010). "Congressional Record—Senate". United States Government Publishing Office.
128. McMahon, Barbara. (May 19, 2008). "Australia cancer deaths linked to Agent Orange". The Guardian.
129. Levant, Victor. (November 13, 2011). "Vietnam War". Historica Canada.
130. (September 13, 2007). "People angry with Agent Orange package turn to class-action lawsuit". Amherst Daily News.
131. "Agent Orange Class Action". Merchant Law Group.
132. Berry, Shawn. (August 4, 2009). "Moncton judge rules in Agent Orange lawsuit". Times & Transcript.
133. "Veterans Affairs Canada Agent Orange Benefits Rev 1.0".
134. (2024-03-02). "Canadian study into Agent Orange use at Gagetown base was incorrect, biased, says U.S. inquiry". The Globe and Mail.
135. Zlomislic, Diana. (February 17, 2011). "Agent Orange "soaked" Ontario teens". The Star.
136. Zlomislic, Diana. (February 17, 2011). "Ontario probes Agent Orange poisoning". The Star.
137. (September 25, 2013). "Were Vets Who Served in Guam Exposed to Agent Orange and Denied Benefits?". The Daily Beast.
138. "Agent Orange: Information for Veterans Who Served in Vietnam". United States Department of Veterans Affairs.
139. (26 January 2006). "Agent Orange Makers Lose S. Korea Suit".
140. (2006-01-26). "Korea orders Agent Orange payments".
141. (May 13, 2011). "Military Secrets Exposed". KPHO-TV.
142. [[Title 38 of the Code of Federal Regulations. link. (May 19, 2021)
143. (4 July 2014). "At a price: manufacturing Agent Orange in NZ?".
144. (November 25, 2006). "Concern prompts review of Dioxin study". New Zealand Herald.
145. (18 September 2022). "Chemical giant Corteva commits to total clean-up of controversial New Plymouth site".
146. (January 1972). "Preliminary Proposals for the Study of Persistence of Herbicides in Forest and Mangrove Soil". Committee on the Effect of Herbicides in Vietnam, National Academy of Sciences.
147. Young, Alvin L.. (January 2013). "Investigations into Allegations of Herbicide Orange on Okinawa, Japan". United States Department of Defence.
148. (March 1, 1978). "Final report of the Federal Task Force for Hazardous Materials Management of the Western Federal Regional Council Region IX, August 1, 1973 to June 30, 1977". US Environmental Protection Agency.
149. EarthTech. (April 2005). "Phase II Environmental Baseline Survey, Johnston Atoll".
150. (February 10, 2014). "Entitlement to service connection for diabetes mellitus, claimed as due to herbicide exposure or ionizing radiation.". United States Department of Veterans Affairs.
151. Mitchell, Jon. (June 4, 2013). "As evidence of agent orange in Okinawa stacks up US sticks with blanket denial". Japan Times.
152. (2003). "An Ecological Assessment of Johnston Atoll". Chemical Materials Agency, United States Department of the Army.
153. Darrow, Robert A.. (September 1971). "Historical, Logistical, Political and Technical Aspects of the Herbicide/Defoliant Program, 1967–1971". Plant Sciences Laboratories, United States Army Chemical Corps.
154. Mitchell, Jon. (January 14, 2012). "'Herbicide Stockpile' at Kadena Air Base, Okinawa: 1971 U.S. Army report on Agent Orange". The Asia-Pacific Journal: Japan Focus.
155. (May 26, 1999). "Agent Orange Found Under Resort Airport". Chicago Tribune.
156. Sakanond, Boonthan. (May 19, 1999). "Thailand: Toxic Legacy of the Vietnam War".
157. "Thailand Military Bases and Agent Orange Exposure – Public Health". [[United States Department of Veterans Affairs]].
158. (March 27, 2005). "University vulnerable to pitfalls of secret experiments". Honolulu Star-Bulletin.
159. "Public Health. Herbicide Tests and Storage Outside Vietnam". United States Department of Veterans Affairs.
160. "Agent Orange Residue on Post-Vietnam War Airplanes". United States Department of Veterans Affairs.
161. Nicosia, Gerald. (2004). "Home to War: A History of the Vietnam Veterans' Movement". Carroll & Graf.
162. "The defoliant Agent Orange, which contains dioxin, was sprayed...". United Press International.
163. {{Cite Q. Q114385850
164. "Report on DoD Herbicides Outside of Vietnam". United States Department of Veterans Affairs.
165. Kaskey, Jack. (February 24, 2012). "Monsanto Settles West Virginia Lawsuits Over Nitro Plant". Bloomburg.
166. (November 22, 2013). "Supreme Court affirms Monsanto pollution settlement in Nitro". Charleston Gazette-Mail.
167. (October 18, 2016). "Vietnam, US launch Danang dioxin clean-up". Phys.org.
168. Ho, Binh Minh. (August 9, 2012). "U.S. starts its first Agent Orange cleanup in Vietnam". Reuters.
169. Campen, Natalie. (July 9, 2013). "Agent Orange clean at Navy Seabee base is the focus at public meeting". WLOX.
170. ((Federal Facilities Assessment Branch, Division of Health Assessment and Consultation, Agency for Toxic Substances and Disease Registry)). (April 2005). "Public Health Assessment, Naval Construction Battalion Center Gulfport, Mississippi, Facility No. MS2170022626".
171. (October 4, 2016). "Dioxins and their effects on human health".