Adenosine reuptake inhibitor

List of AdoRIs

• Acadesine
• Acetate
• Barbiturates
• Benzodiazepines
• Calcium channel blockers
• Carbamazepine
• Carisoprodol
• Cilostazol
• Cyclobenzaprine
• Dilazep
• Dipyridamole
• Estradiol
• Ethanol
• Flumazenil
• Hexobendine
• Hydroxyzine
• Indomethacin
• Inosine
• KF24345
• Meprobamate
• Nitrobenzylthioguanosine
• Nitrobenzylthioinosine
• Papaverine
• Pentoxifylline
• Phenothiazines
• Phenytoin
• Progesterone
• Propentofylline
• Propofol
• Puromycin
• R75231
• RE 102 BS
• Soluflazine
• Toyocamycin
• Tracazolate
• Tricyclic antidepressants

References

References

1. (2004). "Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep". Biochem Pharmacol.
2. (2004). "Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1". Biochem J.
3. (2004). "The adenosine transporter, mENT1, is a target for adenosine receptor signaling and protein kinase Cepsilon in hypoxic and pharmacological preconditioning in the mouse cardiomyocyte cell line, HL-1". J Pharmacol Exp Ther.
4. (2006). "[The mechanisms of depression by benzodiazepines, barbiturates and propofol of excitatory synaptic transmissions mediated by adenosine neuromodulation]". Masui.
5. (2000). "The involvement of adenosine neuromodulation in pentobarbital-induced field excitatory postsynaptic potentials depression in rat hippocampal slices". Anesth Analg.
6. (1982). "Benzodiazepines are weak inhibitors of [3H]nitrobenzylthioinosine binding to adenosine uptake sites in brain". Neurosci Lett.
7. (1982). "The effect of diazepam on adenosine uptake and adenosine-stimulated adenylate cyclase in guinea-pig brain". [[Can J Physiol Pharmacol]].
8. (1999). "Sensitization by chronic diazepam treatment of A2A adenosine receptor-mediated relaxation in rat pulmonary artery". Life Sci.
9. (2008). "Adenosine and adenosine uptake inhibitors potentiate the neuromuscular blocking action of rocuronium mediated by adenosine A(1) receptors in isolated rat diaphragms". Acta Anaesthesiol Scand.
10. (1986). "Similarities of adenosine uptake systems in astrocytes and neurons in primary cultures". Neurochem Res.
11. (1988). "Potentiation of adenosine-evoked depression of rat cerebral cortical neurons by triazolam". Brain Res.
12. (1984). "A purinergic component in the central actions of meprobamate". Eur J Pharmacol.
13. (1985). "A possible role of endogenous adenosine in the sedative action of meprobamate". Eur J Pharmacol.
14. (2009). "[Carisoprodol-mediated modulation of GABAA receptors: in vitro and in vivo studies". J Pharmacol Exp Ther.
15. (2001). "Interplay between inhibition of adenosine uptake and phosphodiesterase type 3 on cardiac function by cilostazol, an agent to treat intermittent claudication". J Cardiovasc Pharmacol.
16. (1982). "The effect of various centrally active drugs on adenosine uptake by the central nervous system". Comp Biochem Physiol C.
17. Phillis J.W.. (1984). "Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants". Br J Pharmacol.
18. (1993). "Lack of efficacy of the adenosine reuptake inhibitor dipyridamole in the treatment of anxiety disorders". Biol Psychiatry.
19. (1985). "Estradiol and progesterone potentiate adenosine's depressant action on rat cerebral cortical neurons". Gen Pharmacol.
20. (2009). "Ethanol Blocks Adenosine Uptake via Inhibiting the Nucleoside Transport System in Bronchial Epithelial Cells". Alcohol Clin Exp Res.
21. (1985). "Solubilization of an adenosine uptake site in brain". J Neurochem.
22. (1983). "Inhibition of adenosine uptake into rat brain synaptosomes by prostaglandins, benzodiazepines and other centrally active compounds". Gen Pharmacol.
23. (1989). "Effect of inosine on pial arterioles: potentiation of adenosine-induced vasodilation". Am J Physiol.
24. (2002). "KF24345, an adenosine uptake inhibitor, ameliorates the severity and mortality of lethal acute pancreatitis via endogenous adenosine in mice". Eur J Pharmacol.
25. (1985). "Inhibitory effect of adenosine on electrically evoked contractions in the rat vas deferens: pharmacological characterization". Neurosci Lett.
26. (1982). "[3H]nitrobenzylthioinosine binding as a probe for the study of adenosine uptake sites in brain". J. Neurochem..
27. (1984). "Behavioral interaction of adenosine and methylxanthines on central purinergic systems". Neurosci Lett.
28. (1999). "Chronic effects of xanthines on levels of central receptors in mice". Cell Mol Neurobiol.
29. Phillis J.W.. (1985). "Chlorpromazine and trifluoperazine potentiate the action of adenosine on rat cerebral cortical neurons". Gen Pharmacol.
30. Phillis J.W.. (1984). "Interactions of the anticonvulsants diphenylhydantoin and carbamazepine with adenosine on cerebral cortical neurons". Epilepsia.
31. (1990). "Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia". Br J Pharmacol.
32. (2004). "The anticonvulsant action of propofol on epileptiform activity in rat hippocampal slices". Anesth Analg.
33. (2002). "Adenosine uptake inhibition ameliorates cerulein-induced acute pancreatitis in mice". Pancreas.
34. (1986). "Mechanism of the antiplatelet action of dipyridamole in whole blood: modulation of adenosine concentration and activity". Thromb Haemost.
35. (1992). "Age-dependence of effects of A1 adenosine receptor antagonism in rat hippocampal slices". J Neurophysiol.
36. (1993). "The effects of the adenosine reuptake inhibitor soluflazine on synaptic potentials and population hypoxic depolarizations in area CA1 of rat hippocampus in vitro". Neuropharmacology.