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8-Hydroxygeraniol dehydrogenase
Class of enzymes
Class of enzymes
| Field | Value |
|---|---|
| Name | 8-Hydroxygeraniol dehydrogenase |
| EC_number | 1.1.1.324 |
8-hydroxygeraniol dehydrogenase (, 8-hydroxygeraniol oxidoreductase, CYP76B10, G10H, CrG10H, SmG10H, acyclic monoterpene primary alcohol:NADP+ oxidoreductase) is an enzyme with systematic name (6E)-8-hydroxygeraniol:NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction
: (6E)-8-hydroxygeraniol + 2 NADP+ \rightleftharpoons (6E)-8-oxogeranial + 2 NADPH + 2 H+ (overall reaction)
: (1a) (6E)-8-hydroxygeraniol + NADP+ \rightleftharpoons (6E)-8-hydroxygeranial + NADPH + H+ : (1b) (6E)-8-hydroxygeraniol + NADP+ \rightleftharpoons (6E)-8-oxogeraniol + NADPH + H+ : (1c) (6E)-8-hydroxygeranial + NADP+ \rightleftharpoons (6E)-8-oxogeranial + NADPH + H+ : (1d) (6E)-8-oxogeraniol + NADP+ \rightleftharpoons (6E)-8-oxogeranial + NADPH + H+
This enzyme contains Zn2+. It catalyses the oxidation of (6E)-8-hydroxygeraniol to (6E)-8-oxogeranial via either (6E)-8-hydroxygeranial or (6E)-8-oxogeraniol.
References
References
- (February 1991). "Acyclic monoterpene primary alcohol:NADP+ oxidoreductase of Rauwolfia serpentina cells: the key enzyme in biosynthesis of monoterpene alcohols". Journal of Biochemistry.
- (April 1995). "Purification and characterization of an acyclic monoterpene primary alcohol:NADP+ oxidoreductase from catmint (Nepeta racemosa)". Archives of Biochemistry and Biophysics.
- {{KEGG enzyme. 1.1.1.324
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