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general/5-ht2c-antagonists

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6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide

Chemical compound


Chemical compound

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6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.

References

References

  1. (November 2011). "A 5-HT(2C) receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference". Neuroscience Letters.
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