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general/n-n-dialkyltryptamines

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5,N,N-TMT

Chemical compound


Chemical compound

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5,N,N-Trimethyltryptamine (5,N,N-TMT; 5-TMT), also known as 5-methyl-DMT, is a tryptamine derivative that may be a psychedelic drug. It was first made in 1958 by Edwin H. P. Young. In animal experiments it was found to be in between DMT and 5-MeO-DMT in potency.

Chemistry

Analogues

Analogues of 5,N,N-TMT include dimethyltryptamine (DMT), 5-methyltryptamine, 5-ethyl-DMT, 5-MeO-DMT, 5-fluoro-DMT, 5-chloro-DMT, 5-bromo-DMT, 1-methyl-DMT, 2-methyl-DMT, 4-methyl-DMT, 6-methyl-DMT, and 7-methyl-DMT, among others.

Society and culture

United States

5,N,N-TMT is not scheduled at the federal level in the United States, but it could be considered an analog of 5-MeO-DMT, in which case, sales or possession intended for human consumption could be prosecuted under the Federal Analog Act.

References

References

  1. (1958). "704. The synthesis of 5-hydroxytryptamine (serotonin) and related tryptamines.". Journal of the Chemical Society (Resumed).
  2. (April 1979). "Serotonin receptor binding affinities of tryptamine analogues". Journal of Medicinal Chemistry.
  3. (1980). "Hallucinogenic agents as discriminative stimuli: a correlation with serotonin receptor affinities". Psychopharmacology.
  4. "§ 1308.11 Schedule I.".
  5. (2022-02-17). "§ 1308.11 Schedule I.".
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