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general/5-ht6-agonists

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5-Benzyloxytryptamine

Chemical compound


Chemical compound

5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors, and an antagonist of TRPM8.

Society and culture

Singapore

5-Benzyloxytryptamine is illegal in Singapore.

References

References

  1. (January 1988). "Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens". European Journal of Pharmacology.
  2. (1991). "5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent". Life Sciences.
  3. (January 1992). "Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins". European Journal of Pharmacology.
  4. (1997). "Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells". Neuropharmacology.
  5. (December 2010). "5-benzyloxytryptamine as an antagonist of TRPM8". Bioorganic & Medicinal Chemistry Letters.
  6. "Misuse of Drugs Act - Singapore Statutes Online".
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