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4-Pyrone
4-Pyranone
4-Pyrone (γ-pyrone or pyran-4-one) is an unsaturated cyclic chemical compound with the molecular formula C5H4O2.It is isomeric with 2-pyrone.
Preparation
4-Pyrone is prepared via the thermal decarboxylation of chelidonic acid.
Reactions
4-Pyrone and its derivatives react with amines in protic solvents to form 4-Pyridones.
Derivatives
4-Pyrone forms the central core of several natural chemical compounds, including maltol, meconic acid, kojic acid, and of the important class of the flavones.
:{| class="wikitable" |[[Image:Maltol.svg|70px]] |[[Image:KojicAcid.png|120px]] |- | Maltol | Kojic acid |}
References
References
- [http://www.sigmaaldrich.com/catalog/search/ProductDetail/ALDRICH/177229 4H-Pyran-4-one] at [[Sigma-Aldrich]]
- (1972). "Weygand/Hilgetag Preparative Organic Chemistry". John Wiley & Sons, Inc..
- (1971). "Reactions of 4-pyrones with primary amines. A new class of ionic associates". Journal of Heterocyclic Chemistry.
- (1963). "The Preparation, Properties, and Structure of 2,6-bis-(Alkyamino)-2,5-heptadien-4-ones". Canadian Journal of Chemistry.
- (2009). "Γ-Pyrone natural products—A privileged compound class provided by nature". Bioorganic & Medicinal Chemistry.
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