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3-Nitrobenzaldehyde

| NFPA-H = 2 | NFPA-F = 1 | NFPA-R = 0 | NFPA-S =

3-Nitrobenzaldehyde is an organic compound with the formula . It is one of three isomers of nitrobenzaldehyde. It contains a nitro group meta-substituted to the aldehyde.

3-Nitrobenzaldehyde is the primary product obtained via the mono-nitration of benzaldehyde with nitric acid. : Product distribution is about 19% for the ortho-, 72% for the meta- and 9% for the para isomers.

Uses

3-Nitrobenzaldehyde is a precursor to the drug Tipranavir. It is a mainstay in the synthesis of Dihydropyridine calcium channel blockers. Via selective reduction of the nitro group, it is a precursor to the diazonium salt.

References

References

  1. [http://chemicalland21.com/specialtychem/finechem/3-NITROBENZALDEHYDE.htm 3-Nitrobenzaldehyde]
  2. "3-Nitrobenzaldehyde MSDS".
  3. (2011). "Ullmann's Encyclopedia of Industrial Chemistry".
  4. Johannes S. Buck and Walter S. Ide. (1933). "''m''-Chlorobenzaldehyde". Organic Syntheses.
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benzaldehydes nitrobenzene-derivatives
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