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3-Hydroxyvaleric acid

β-Hydroxypentanoic acid

3-Hydroxyvaleric acid (3-hydroxypentanoic acid) is the organic compound with the formula . It is one of the hydroxypentanoic acids. It is made from odd carbon fatty acids in the liver and rapidly enters the brain. As opposed to 4-carbon ketone bodies, 3-hydroxyvaleric acid is anaplerotic, meaning it can refill the pool of TCA cycle intermediates. The triglyceride triheptanoin is used clinically to produce 3-hydroxyvalerate (the carboxylate form).

Properties

  • Solubility in water: 784.8 g/L at 25 °C (estimated)

References

References

  1. (2000). "Hydroxycarboxylic Acids, Aliphatic".
  2. Renée P. Kinman. (2006). "Parenteral and Enteral Metabolism of Anaplerotic Triheptanoin in Normal Rats". Am J Physiol Endocrinol Metab.
  3. "Human Metabolome Database: Showing metabocard for 3-Hydroxyvaleric acid (HMDB0000531)".
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beta-hydroxycarboxylic-acids
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