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3-Fluoroethamphetamine

Stimulant drug of the amphetamine class

Stimulant drug of the amphetamine class

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3-Fluoroethamphetamine (3-FEA) is a stimulant drug of the amphetamine class which acts as a releasing agent of the monoamine neurotransmitters norepinephrine, dopamine and serotonin.

Compared to the unsubstituted ethylamphetamine, 3-fluoroethamphetamine is a weaker releaser of noradrenaline, but a stronger releaser of both dopamine and serotonin, and produced the strongest reinforcing effects in animal studies out of a range of 3-substituted ethamphetamine derivatives tested, despite not being the most potent dopamine releaser.

References

References

  1. (1974). "Structural relationship between meta-substituted N-ethylamphetamines and self-administration in rhesus monkeys.". Pharmacologist.
  2. (February 1975). "Structure-activity relationships between meta-substituted N-ethylamphetamines and locomotor activity in mice". The Journal of Pharmacology and Experimental Therapeutics.
  3. (May 1976). "Specificity of release of biogenic amines from isolated rat brain tissue as a function of the meta substituent of N-ethylamphetamine derivatives". The Journal of Pharmacology and Experimental Therapeutics.
  4. (May 1978). "meta Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships". The Journal of Pharmacology and Experimental Therapeutics.
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designer-drugs 3-fluorophenyl-compounds serotonin-norepinephrine-dopamine-releasing-agents stimulants substituted-amphetamines
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