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3-dehydroquinate synthase II

Class of enzymes


Class of enzymes

FieldValue
Name3-dehydroquinate synthase II
EC_number1.4.1.24

3-dehydroquinate synthase II (, DHQ synthase II, MJ1249 (gene), aroB' (gene)) is an enzyme with systematic name 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD+ oxidoreductase (deaminating). This enzyme catalyses the following chemical reaction

The three substrates of this enzyme are 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid (1), water, and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 3-dehydroquinic acid, ammonia, reduced NADH, and a proton. It was isolated from the archaeon Methanocaldococcus jannaschii.

References

References

  1. (June 2004). "L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii". Biochemistry.
  2. {{KEGG enzyme. 1.4.1.24
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