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3,4-Xylidine


3,4-Dimethylbenzenamine

3,4-Xylidine is an organic compound with the formula C6H3(CH3)2NH2. It is one of several isomeric xylidines. It is a colorless solid. It is a precursor for the production of riboflavin (vitamin B2).

The compound is prepared by two routes: hydrogenation of (2-chloromethyl)-4-nitrotoluene and reaction of the bromoxylene with ammonia.

Safety

Like other xylidines, 3,4-xylidine has modest toxicity with an of 812 mg/kg when administered orally to rats.

In 2003, more than twenty US Army troops were allegedly exposed to 3,4-xylidine during the occupation of Iraq, leading to a number of health complaints.

References

References

  1. M. Meyer. (2012). "Xylidines". Wiley-VCH.
  2. (May 14, 2015). "12 Years Later, a Mystery of Chemical Exposure in Iraq Clears Slightly". New York Times.
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