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3,3-Diphenylcyclobutanamine

Stimulant drug


Stimulant drug

FieldValue
verifiedrevid477217189
IUPAC_name3,3-diphenylcyclobutan-1-amine
image3,3-Diphenylcyclobutanamine.svg
image_classskin-invert-image
legal_statusUncontrolled
CAS_number_Ref
CAS_number64895-45-0
UNII_Ref
UNIICN43PDA78X
ATC_prefixnone
PubChem47486
ChemSpiderID_Ref
ChemSpiderID43204
C16H=17N=1
smilesc1ccc(cc1)C3(c2ccccc2)CC(N)C3
StdInChI_Ref
StdInChI1S/C16H17N/c17-15-11-16(12-15,13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,15H,11-12,17H2
StdInChIKey_Ref
StdInChIKeyIABBZBVTZRKDFW-UHFFFAOYSA-N

| elimination_half-life =

3,3,-Diphenylcyclobutanamine is a psychostimulant drug which was originally prepared as an antidepressant in the late 1970s. It appears to inhibit the reuptake of serotonin, norepinephrine, and dopamine, and may also induce their release as well. The N-methyl and N,N-dimethyl analogues of the compound are also known and are more potent. All three agents produce locomotor stimulation in animal studies, with the tertiary amine being the strongest.

References

References

  1. (January 1978). "Antidepressant agents. 9. 3,3-Diphenylcyclobutylamines, a new class of central stimulants". Journal of Medicinal Chemistry.
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