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2C-T-9

Field	Value
image	2C-T-9 v2.svg
image_class	skin-invert-image
width	250px
routes_of_administration	Oral
class	Serotonin [5-HT2A receptor](5-ht2a-receptor) agonist; Serotonergic psychedelic; Hallucinogen
ATC_prefix	None
duration_of_action	12–18 hours
CAS_number	207740-28-1
PubChem	44349799
ChemSpiderID	23206245
synonyms	4-tert-Butylthio-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-tert-butylthiophenethylamine
C	14	H=23	N=1	O=2	S=1
SMILES	NCCc1cc(OC)c(cc1OC)SC(C)(C)C
StdInChI	1S/C14H23NO2S/c1-14(2,3)18-13-9-11(16-4)10(6-7-15)8-12(13)17-5/h8-9H,6-7,15H2,1-5H3
StdInChIKey	PSVDMTZXLJTPNX-UHFFFAOYSA-N

| Drugs.com =

| elimination_half-life =

2C-T-9, also known as 4-tert-butylthio-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally.

Use and effects

According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved), the dose range of 2C-T-9 is 60 to 100mg and its duration is 12 to 18hours. Its effects included impairment such that one would not feel comfortable to drive, more effects "to the body than to the head", "body energy", sleeping difficulties, and hangover. The drug did not produce psychedelic visuals. One of the reports of 2C-T-9 was rated as a '+++' on the Shulgin Rating Scale.

Interactions

Pharmacology

Pharmacodynamics

2C-T-9 has been found to act as a serotonin 5-HT2A receptor agonist with modest potency ( = 150nM). The drug failed to produce the head-twitch response, a behavioral proxy of psychedelic effects, in rodents at the assessed dose of 3mg/kg, which was said to parallel its known low potency in humans.

History

2C-T-9 was first described in the scientific literature by Alexander Shulgin and colleagues in 1991. This included in a journal article and in his book PiHKAL (Phenethylamines I Have Known and Loved).

Society and culture

Legal status

Canada

2C-T-9 is a controlled substance in Canada under phenethylamine blanket-ban language.

References

{{CitePiHKAL
(2003). "Hallucinogens: A Forensic Drug Handbook". Elsevier Science.
(January 1991). "Central nervous system (CNS) activity of two new psychoactive compounds". Journal of Psychoactive Drugs.
(1994). "Hallucinogens: An Update". National Institute on Drug Abuse.
(April 2024). "Synthesis and Structure-Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT2 Receptor Agonist". J Med Chem.
"Controlled Drugs and Substances Act".

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

2c-(psychedelics) 5-ht2a-agonists pihkal psychedelic-phenethylamines tert-butyl-compounds thioethers

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