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2C-O-4
| Field | Value | |||
|---|---|---|---|---|
| Verifiedfields | changed | |||
| Watchedfields | changed | |||
| verifiedrevid | 477216433 | |||
| image | 2C-O-4-Chemdraw.png | |||
| image_class | skin-invert-image | |||
| width | 250px | |||
| image2 | 2C-O-4-3d-sticks.png | |||
| image_class2 | bg-transparent | |||
| width2 | 250px | |||
| routes_of_administration | Oral | |||
| ATC_prefix | None | |||
| duration_of_action | A few hours | |||
| CAS_number_Ref | ||||
| CAS_number | 952006-65-4 | |||
| PubChem | 44719510 | |||
| ChemSpiderID_Ref | ||||
| ChemSpiderID | 21106225 | |||
| UNII | 1GFL65O0VB | |||
| synonyms | 4-Isopropoxy-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-isopropoxyphenethylamine | |||
| IUPAC_name | 2-{2,5-Dimethoxy-4-[(propan-2-yl)oxy]phenyl}ethan-1-amine | |||
| C | 13 | H=21 | N=1 | O=3 |
| SMILES | CC(C)Oc1cc(OC)c(cc1OC)CCN | |||
| StdInChI_Ref | ||||
| StdInChI | 1S/C13H21NO3/c1-9(2)17-13-8-11(15-3)10(5-6-14)7-12(13)16-4/h7-9H,5-6,14H2,1-4H3 | |||
| StdInChIKey_Ref | ||||
| StdInChIKey | KAKXJLWAEMHHTL-UHFFFAOYSA-N |
| Drugs.com =
| elimination_half-life =
2C-O-4, also known as 4-isopropoxy-2,5-dimethoxyphenethylamine, is a phenethylamine of the 2C family. It is also a positional isomer of isoproscaline and was probably first synthesized by Alexander Shulgin. It produces hallucinogenic or psychedelic effects. Because of the low potency of 2C-O-4, and the inactivity of 2C-O, Shulgin felt that the 2C-O series would not be an exciting area for research, and did not pursue any further analogues.
Use and effects
Little is known about the psychopharmacological effects of 2C-O-4. Based on the one report available in his book PiHKAL, Shulgin lists the dose of 2C-O-4 as being greater than 60mg orally. At 60mg, threshold psychoactive effects occurred. These included awareness of something in the front part of the head, yawning, physiological changes, and a general exhilaration and excitement. The effects lasted a few hours and were rated as a +1 on the Shulgin Rating Scale. The drug was regarded as remaining to be fully explored.
Interactions
Pharmacology
Pharmacodynamics
The pharmacology of 2C-O-4 analogues has been studied.
Chemistry
2C-O-4 is in a class of compounds commonly known as phenethylamines, and the systematic chemical name is 2-(4-isopropoxy-2,5-dimethoxyphenyl)ethanamine.
Society and culture
Legal status
Canada
As of October 31, 2016, 2C-O-4 is a controlled substance (Schedule III) in Canada.
United States
2C-O-4 is unscheduled and unregulated in the United States; however, because of its close similarity in structure and effects to mescaline and 2C-T-7, possession and sale of 2C-O-4 may be subject to prosecution under the Federal Analog Act.
References
References
- {{CitePiHKAL [http://www.erowid.org/library/books_online/pihkal/pihkal035.shtml 2C-O-4 Entry in PiHKAL]
- (2019). "Receptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines". Front Pharmacol.
- (4 May 2016). "Canada Gazette – Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)".
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