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2C-G
| Field | Value | |||
|---|---|---|---|---|
| Verifiedfields | changed | |||
| Watchedfields | changed | |||
| verifiedrevid | 477216206 | |||
| image | 2C-G.svg | |||
| image_class | skin-invert-image | |||
| width | 200px | |||
| image2 | 2C-G-3d-sticks.png | |||
| image_class2 | bg-transparent | |||
| width2 | 175px | |||
| routes_of_administration | Oral | |||
| class | Serotonergic psychedelic; Hallucinogen | |||
| ATC_prefix | None | |||
| legal_status | In general Unscheduled | |||
| duration_of_action | 18–30 hours | |||
| CAS_number_Ref | ||||
| CAS_number | 207740-18-9 | |||
| PubChem | 22238091 | |||
| ChemSpiderID_Ref | ||||
| ChemSpiderID | 21106224 | |||
| UNII_Ref | ||||
| UNII | DTG7FMO01J | |||
| ChEMBL_Ref | ||||
| ChEMBL | 127202 | |||
| synonyms | 2C-G-0; 2,5-Dimethoxy-3,4-dimethylphenethylamine; 3,4-Dimethyl-2,5-dimethoxyphenethylamine; 3-Methyl-2C-D | |||
| IUPAC_name | 2-(2,5-dimethoxy-3,4-dimethylphenyl)ethan-1-amine | |||
| C | 12 | H=19 | N=1 | O=2 |
| SMILES | COc1c(C)c(C)c(cc1CCN)OC | |||
| StdInChI_Ref | ||||
| StdInChI | 1S/C12H19NO2/c1-8-9(2)12(15-4)10(5-6-13)7-11(8)14-3/h7H,5-6,13H2,1-4H3 | |||
| StdInChIKey_Ref | ||||
| StdInChIKey | NFOHGLKGLZIHJQ-UHFFFAOYSA-N |
| Drugs.com =
| elimination_half-life =
2C-G, or 2C-G-0, also known as 3,4-dimethyl-2,5-dimethoxyphenethylamine or as 3-methyl-2C-D, is a psychedelic phenethylamine of the 2C family. First synthesized by Alexander Shulgin, it has structural and pharmacodynamic properties similar to 2C-D and Ganesha (G). The drug has a number of known homologues, which are known as the 2C-G series of compounds.
Use and effects
In Alexander Shulgin's book PiHKAL (Phenethylamines I Have Known and Loved), the dose range is listed as 20 to 35mg orally. Effects are similar to the related Ganesha, and are extremely long lasting; the duration is 18 to 30hours. Visual effects are muted or absent, and it is described as an "insight-enhancer". Unlike other members of the 2C series, 2C-G is nearly as potent as its amphetamine form.
Interactions
Chemistry
Synthesis
The chemical synthesis of 2C-G has been described.
Homologues
Several homologues of 2C-G (2C-G-0) were also synthesized and/or tested by Alexander Shulgin. These include 2C-G-3, 2C-G-5, and 2C-G-N. Some, such as 2C-G-1, 2C-G-2, 2C-G-4, and 2C-G-6, are possible to synthesize in principle but impossible or extraordinarily difficult to do so in practice.
| Compound | Details | Structure |
|---|---|---|
| 2C-G-1 | *CAS #*: 2888537-47-9 | |
| [[File:2C-G-1.png | 125px | class=skin-invert-image]] |
| 2C-G-2 | *CAS #*: 2888537-48-0 | |
| [[File:2C-G-2.png | 125px | class=skin-invert-image]] |
| [2C-G-3](2c-g-3) | *CAS #*: 207740-19-0 | |
| [[File:2C-G-3-Chemdraw.png | 125px | class=skin-invert-image]] |
| [2C-G-4](2c-g-4) | *CAS #*: 952006-59-6 | |
| [[File:2C-G-4.svg | 125px | class=skin-invert-image]] |
| [2C-G-5](2c-g-5) | *CAS #*: 207740-20-3 | |
| [[File:2C-G-5.svg | 125px | class=skin-invert-image]] |
| 2C-G-6 | *CAS #*: 2888537-49-1 | |
| [[File:2C-G-6.png | 125px | class=skin-invert-image]] |
| [2C-G-N](2c-g-n) | *CAS #*: 207740-21-4 | |
| [[File:2C-G-N-Chemdraw.png | 125px | class=skin-invert-image]] |
History
2C-G was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).
Society and culture
Legal status
Canada
As of October 31, 2016; 2C-G is a controlled substance (Schedule III) in Canada.
United Kingdom
2C-G and all other compounds featuring in PiHKAL are Class A drugs in the United Kingdom.
United States
In the United States 2C-G is considered a Schedule I controlled substance as a positional isomer of 2C-E and DOM.
References
References
- (1991). "PiHKAL: A Chemical Love Story". Transform Press.
- (4 May 2016). "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)".
- (February 2023). "Lists of: Scheduling Actions - Controlled Substances - Regulated Chemicals". Drug Enforcement Administration.
- [[Drug Enforcement Administration]]. (3 December 2007). "Definition of “Positional Isomer” as It Pertains to the Control of Schedule I Controlled Substances".
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