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general/2-alkyltryptamines

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2-Me-DET

Chemical compound


Chemical compound

FieldValue
image2-Me-DET structure.svg
image_classskin-invert-image
width225px
image22-Me-DET 3D.png
image_class2bg-transparent
width2200px
routes_of_administrationOral
classPsychoactive drug; Serotonergic psychedelic; Hallucinogen
ATC_prefixNone
duration_of_action6–8 hours
CAS_number26628-88-6
UNII_Ref
UNIISSF4F77CV3
PubChem33561
ChemSpiderID30962
synonyms2-Methyl-DET; 2-Methyl-*N*,*N*-diethyltryptamine
IUPAC_nameN,N-diethyl-2-(2-methyl-1H-indol-3-yl)ethanamine
C15H=22N=2
SMILESCCN(CC)CCc1c(C)[nH]c2ccccc12
StdInChI1S/C15H22N2/c1-4-17(5-2)11-10-13-12(3)16-15-9-7-6-8-14(13)15/h6-9,16H,4-5,10-11H2,1-3H3
StdInChIKeyVVUATPWGKMGHGM-UHFFFAOYSA-N

| Drugs.com =

| elimination_half-life =

2-Me-DET, or 2-methyl-DET, also known as 2-methyl-N,N-diethyltryptamine, is a psychedelic drug of the tryptamine family. It is the 2-methyl derivative of diethyltryptamine (DET). The drug is taken orally.

Use and effects

In his book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin lists 2-Me-DET's dose as 80 to 120mg orally and its duration as 6 to 8hours. The effects of 2-Me-DET have been reported to include a vague unreal feeling, clouding and slowing of thoughts, DiPT-like sound distortion including higher pitches of music sounding muffled and tones shifting to a lower frequency, and stomach ache.

Interactions

Chemistry

Synthesis

The chemical synthesis of 2-Me-DET has been described.

Analogues

Analogues of 2-Me-DET include 2-methyltryptamine (2-MT; 2-Me-T), 2-methyl-DMT (2-Me-DMT; 2,N,N-TMT), 2-methyl-5-MeO-DMT (5-MeO-2,N,N-TMT), and 2-methyl-AMT (2-Me-AMT; 2,α-DMT).

History

2-Me-DET was first described in the scientific literature by R. B. Barlow and I. Khan in 1959. Subsequently, it was described in greater detail by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved).

References

References

  1. {{CiteTiHKAL
  2. (March 1959). "Actions of some analogues of tryptamine on the isolated rat uterus and on the isolated rat fundus strip preparations". Br J Pharmacol Chemother.
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