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2-Iodobenzoic acid

2-Iodobenzoic acid

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2-Iodobenzoic acid, or o-iodobenzoic acid, is an isomer of iodobenzoic acid. The synthesis of 2-iodobenzoic acid via the diazotization of anthranilic acid is commonly performed in university organic chemistry labs. One of its most common uses is as a precursor for the preparation of IBX and Dess–Martin periodinane, both used as mild oxidants.

Synthesis

2-Iodobenzoic acid can be synthesized by a Sandmeyer reaction: the diazotization of anthranilic acid followed by a reaction with iodide.

Diazo replacement of anthranilic acid.

References

References

  1. "2-Iodobenzoic acid".
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