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2-Hydroxymuconate-6-semialdehyde dehydrogenase
Class of enzymes
Class of enzymes
| Field | Value |
|---|---|
| Name | 2-Hydroxymuconate-6-semialdehyde dehydrogenase |
| EC_number | 1.2.1.85 |
2-Hydroxymuconate-6-semialdehyde dehydrogenase (, * [gene], * [gene] ) is an enzyme with systematic name (2E,4Z)-2-hydroxy-6-oxohexa-2,4-dienoate:NAD+ oxidoreductase. This enzyme catalyses the following chemical reaction
This substrate for this enzyme is formed by meta ring cleavage of catechol (EC 1.13.11.2, catechol 2,3-dioxygenase), and is an intermediate in the bacterial degradation of several aromatic compounds.
References
References
- (March 1995). "Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product) encoded by TOL plasmid pWW0 of Pseudomonas putida". Journal of Bacteriology.
- (November 2006). "Metabolism of 4-amino-3-hydroxybenzoic acid by Bordetella sp. strain 10d: A different modified meta-cleavage pathway for 2-aminophenols". Bioscience, Biotechnology, and Biochemistry.
- (November 2009). "Uncovering the protocatechuate 2,3-cleavage pathway genes". Journal of Bacteriology.
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