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2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase

Class of enzymes


Class of enzymes

FieldValue
Name2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
EC_number1.1.1.312

2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase (, 2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase, 4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP+ oxidoreductase, alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase, 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase, LigC, ProD) is an enzyme with systematic name 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal:NADP+ 2-oxidoreductase. This enzyme catalyses the following chemical reaction:

Unsubstituted aliphatic or aromatic aldehydes or glucose cannot serve as substrate of this enzyme.

References

References

  1. (April 1978). "Purification and properties of alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase". Journal of Biochemistry.
  2. (December 1979). "Isolation and identification of the reaction product of alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase". Journal of Biochemistry.
  3. (February 1983). "Purification and properties of 2-pyrone-4,6-dicarboxylate hydrolase". Journal of Biochemistry.
  4. (December 2000). "Genetic and biochemical characterization of 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase and its role in the protocatechuate 4,5-cleavage pathway in Sphingomonas paucimobilis SYK-6". Journal of Bacteriology.
  5. {{KEGG enzyme. 1.1.1.312
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