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2-Fluoromethamphetamine

Stimulant designer drug

2-Fluoromethamphetamine (2-FMA) is a stimulant drug of the amphetamine family which has been used as a designer drug. 2-FMA is commonly compared to lisdexamfetamine (Vyvanse), and dextroamphetamine due to its efficacy as a study or productivity aid. 2-FMA is purported to produce somewhat less euphoria than comparable amphetamines, likely due to its main mechanism of action consisting of norepinephrine reuptake inhibition.

Chemistry

2-Fluoromethamphetamine is fluorinated analogue of methamphetamine, and is a regioisomer of 3-FMA and 4-FMA.

It does not activate the serotonin receptors, including 5-HT2A, unlike most stimulant drugs of the amphetamine family.

Legal status

Canada

As of 1996, 2-FMA is a controlled substance in Canada, due to being an analog of methamphetamine.

China

As of October 2015, 2-FMA is a controlled substance in China.

Germany

As of 13 December 2014, 2-FMA is a controlled substance in Germany. It is controlled under Anlage I BtMG (Narcotics Act, Schedule I). Substances controlled under Anlage I BtMG are illegal to manufacture, possess, import, export, buy, sell, procure or dispense without a license. Violations of the law are punishable by a fine or imprisonment for up to five years.

Ukraine

As of July 2019, 2-FMA is a controlled substance in Ukraine (considered a narcotic).

United States

As a close analog of a scheduled controlled substance, sale or possession of 2-FMA could be potentially be prosecuted under the Federal Analogue Act.

References

(April 2010). "Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone". Forensic Science International.
(February 2023). "Identification and Quantitative Analysis of 2-Fluoromethamphetamine and Its Metabolites in Human Urine". Journal of Analytical Toxicology.
(December 2020). "In vitro characterization of new psychoactive substances at the μ-opioid, CB1, 5HT_1A, and 5-HT_2A receptors-On-target receptor potency and efficacy, and off-target effects". Forensic Science International.
Legislative Services Branch. (2022-03-31). "Consolidated federal laws of Canada, Controlled Drugs and Substances Act".
(27 September 2015). "关于印发《非药用类麻醉药品和精神药品列管办法》的通知". China Food and Drug Administration.
"Achtundzwanzigste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften – Vom 5. Dezember 2014". Bundesanzeiger-Verlags-GmbH.
"Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz – BtMG) Anlage I (zu § 1 Abs. 1) (nicht verkehrsfähige Betäubungsmittel)".
"Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz – BtMG) § 29 Straftaten".
(23 July 2019). "Про внесення змін до Закону України "Про обіг в Україні наркотичних засобів, психотропних речовин, їх аналогів і прекурсорів"". Verkhovna Rada of Ukraine.
(March 2005). "Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs)". Forensic Science International.
"Federal Controlled Substance Analogue Act Summary". Erowid Analog Law Vault.

Info: Wikipedia Source

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designer-drugs methamphetamines 2-fluorophenyl-compounds norepinephrine-dopamine-releasing-agents organofluorides

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