Surf Wiki
Save to docs
general/ec-1-4-1

From Surf Wiki (app.surf) — the open knowledge base

2,4-diaminopentanoate dehydrogenase

Class of enzymes

Class of enzymes

FieldValue
Name2,4-diaminopentanoate dehydrogenase
EC_number1.4.1.12
CAS_number39346-26-4
GO_code0047530

In enzymology, 2,4-diaminopentanoate dehydrogenase () is an enzyme that catalyzes the chemical reaction

The substrates of this enzyme are (2R,4S)-2,4-diaminopentanoic acid, water, and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are (2R)-2-amino-4-oxopentanoic acid, reduced NADH, ammonia, and a proton. Nicotinamide adenine dinucleotide phosphate can be used as an alternative cofactor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating). This enzyme is also called 2,4-diaminopentanoic acid C4 dehydrogenase. This enzyme participates in 3 metabolic pathways: lysine degradation, arginine and proline metabolism, and d-arginine and d-ornithine metabolism.

References

References

  1. {{KEGG enzyme. 1.4.1.12
  2. (1973). "2,4-diaminopentanoic acid C 4 dehydrogenase. Purification and properties of the protein". J. Biol. Chem..
  3. Stadtman TC. (1973). "Lysine metabolism by clostridia. XIIB 2,4-Diaminohexanoate dehydrogenase (2,4-diaminopentanoate dehydrogenase)". Adv. Enzymol. Relat. Areas Mol. Biol..
  4. (1970). "Ornithine metabolism by Clostridium sticklandii. Oxidation of ornithine to 2-amino-4-ketopentanoic acid via 2,4-diaminopentanoic acid; participation of B12 coenzyme, pyridoxal phosphate, and pyridine nucleotide". J. Biol. Chem..
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

ec-1.4.1 nadph-dependent-enzymes nadh-dependent-enzymes enzymes-of-unknown-structure
Want to explore this topic further?

Ask Mako anything about 2,4-diaminopentanoate dehydrogenase — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report