1991 Copa Libertadores

Qualified teams

Draw

The champions and runners-up of each football association were drawn into the same group along with another football association's participating teams. Three clubs from Paraguay competed as Olimpia was champion of the 1990 Copa Libertadores. They entered the tournament in the Second round.

Group stage

Group 1

Group 2

Group 3

Group 4

Group 5

• Colombian club teams América, and Atlético Nacional were unable to play at their home venues. Their games were held in Miami, Florida and San Cristóbal, Venezuela.

Round of 16

• The top three teams in every group qualified along with Olimpia the champion of Copa Libertadores 1990
• First leg matches were played on April 16 and April 17, 1991. Second leg matches were played on April 24 and April 25, 1991. |- |}

Quarterfinals

• First leg matches were played on May 1, May 2, and May 3, 1991. Second leg matches played on May 8 and May 10, 1991. |- |}

Semifinals

• First leg matches played on May 16, 1991. Second leg matches played on May 22 and May 23, 1991. |- |}

Finals

Main article: 1991 Copa Libertadores Finals

First leg match played on May 29, 1991, in Asunción, Paraguay at Defensores del Chaco stadium. Second leg final match played on June 5, 1991, in Santiago, Chile at Estadio Monumental David Arellano.

Herrera Colo-Colo won 3-0 on aggregate.

Champion