Surf Wiki
Save to docs
general/5a-reduced-steroid-metabolites

From Surf Wiki (app.surf) — the open knowledge base

19-Norandrosterone

Chemical compound

Chemical compound

| elimination_half-life =

19-Norandrosterone, also known as 5α-estran-3α-ol-17-one, is a metabolite of nandrolone (19-nortestosterone) and bolandione (19-norandrostenedione) that is formed by 5α-reductase. It is on the list of substances prohibited by the World Anti-Doping Agency since it is a detectable metabolite of nandrolone, an anabolic-androgenic steroid (AAS). Consumption of androstendione products contaminated with traces of bolandione may also result in testing positive for nandrolone.

Traces of 19-norandrosterone may be naturally present in human urine. An experiment conducted on athletes showed that after a prolonged intense effort, the 19-norandrosterone concentration can be increased by a factor varying between 2 and 4, but another study failed to replicate the result. Concentration also increases in the urine of female athletes during menstruation. The consumption of edible parts of a non-castrated pig, containing 19-nortestosterone, has been shown to result in the excretion of 19-norandrosterone in the following hours, so athletes should prudently avoid meals composed of pig offal in the hours preceding doping tests. Consumption of boar meat, liver, kidneys and heart also increased 19-norandrosterone output.

References

References

  1. "THE 2007 PROHIBITED LIST INTERNATIONAL STANDARD". [[World Anti-Doping Agency]].
  2. (2000). "Trace contamination of over-the-counter androstenedione and positive urine test results for a nandrolone metabolite". JAMA.
  3. (February 1999). "Evidence for the presence of endogenous 19-norandrosterone in human urine". J. Chromatogr. B.
  4. (September 2002). "Nandrolone excretion is not increased by exhaustive exercise in trained athletes". Med Sci Sports Exerc.
  5. (October 2001). "Endogenous origin of norandrosterone in female urine: indirect evidence for the production of 19-norsteroids as by-products in the conversion from androgen to estrogen". J. Steroid Biochem. Mol. Biol..
  6. Ayotte C. (July 2006). "Significance of 19-norandrosterone in athletes' urine samples". Br J Sports Med.
  7. (2000). "Consequence of boar edible tissue consumption on urinary profiles of nandrolone metabolites. I. Mass spectrometric detection and quantification of 19-norandrosterone and 19-noretiocholanolone in human urine". Rapid Commun. Mass Spectrom..
Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

5α-reduced-steroid-metabolites secondary-alcohols androgens estranes human-drug-metabolites ketones
Want to explore this topic further?

Ask Mako anything about 19-Norandrosterone — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report