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1,4-Dimethoxybenzene

soluble in acetone

1,4-Dimethoxybenzene is an organic compound with the formula CH(OCH). It is one of three isomers of dimethoxybenzene. It is a white solid with an intensely sweet floral odor. It is produced by several plant species.

Occurrence

It occurs naturally in willow (Salix), tea, hyacinth, zucchini (Cucurbita pepo). In a study in mice, Iranian scientists identified 1,4-dimethoxybenzene as the major psychoactive chemical in musk willow (Salix aegyptiaca) by its ability to cause somnolescence and depressed activity.

Preparation

It is produced by the methylation of hydroquinone using dimethylsulfate and an alkali.

Uses

1,4-Dimethoxybenzene is mainly used in perfumes and soaps.

It is an intermediate in synthesis of organic compounds, including pharmaceuticals such as methoxamine and butaxamine.

Niche uses

It can be used as a developer in black and white film, and as a base in synthesizing catecholamines and phenethylamines.

References

References

  1. [http://www.sigmaaldrich.com/catalog/product/aldrich/d131350?lang=en&region=US&cm_sp=Insite--prodRecCold_xviews--prodRecCold10-1] at [[Sigma-Aldrich]]
  2. {{GESTIS
  3. Karl-Georg Fahlbusch, Franz-Josef Hammerschmidt, Johannes Panten, Wilhelm Pickenhagen, Dietmar Schatkowski, Kurt Bauer, Dorothea Garbe and Horst Surburg "Flavors and Fragrances" in ''Ullmann's Encyclopedia of Industrial Chemistry'', 2003, Wiley-VCH. {{doi. 10.1002/14356007.a11_141
  4. It appears to attract bees as it has a powerful response in their [[Antenna (biology). 10.1111/boj.12183
  5. Isaac Karimi. (2011). "Chemical composition and effect of an essential oil of Salix aegyptiaca L. (Musk willow) in hypercholesterolemic rabbit model". Brazilian Journal of Pharmacognosy.
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hydroquinone-ethers o-methylated-natural-phenols sweet-smelling-chemicals
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