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1,1,2-Trichloroethane

vinyl trichloride

symmetrical Trichloroethane monochlorethylen chloride (archaic) | NFPA-H = 3 | NFPA-F = 1 | NFPA-R = 2000 ppm (rat, 4 hr) 1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula and the structural formula . It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture.

It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene.

Toxicity

1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness.

The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-trichloroethane at 10 ppm over an eight-hour time-weighted average.

References

References

  1. {{PGCH. 0628
  2. 1,1,2-Trichloroethane toxicity
  3. {{IDLH. 79005. 1,1,2-Trichloroethane
  4. (March 2021). "Toxicological profile for 1,1,2-trichloroethane". [[Agency for Toxic Substances and Disease Registry]] (ATSDR).
  5. "Safety (MSDS) data for 1,1,2-trichloroethane".
  6. [https://www.cdc.gov/niosh/npg/npgd0628.html CDC - NIOSH Pocket Guide to Chemical Hazards]
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chloroalkanes halogenated-solvents gabaa-receptor-positive-allosteric-modulators sweet-smelling-chemicals
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