Sf21

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title: "Sf21" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["insect-cell-lines", "spodoptera"] description: "Cell line" topic_path: "general/insect-cell-lines" source: "https://en.wikipedia.org/wiki/Sf21" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Cell line ::

::figure[src="https://upload.wikimedia.org/wikipedia/commons/0/0a/Sf21.jpg"] ::

Sf21 (officially called IPLB-Sf21-AE) is a continuous cell line developed from ovaries of the Fall Army worm, Spodoptera frugiperda, a moth species that is an agricultural pest on corn and other grass species. It was originally developed in the United States at the Henry A. Wallace Beltsville Agricultural Research Center. Sf9 is a substrain (clone) of these cells that was isolated from Sf21 by researchers at Texas A&M University.

Both the clone and parent strains of the cells have been extensively used in research on viruses, especially baculoviruses in their use for producing recombinant proteins.

References

::callout[type=info title="Wikipedia Source"] This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page. ::