Randy Schekman

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American cell biologist

title: "Randy Schekman" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["1948-births", "living-people", "nobel-laureates-in-physiology-or-medicine", "american-nobel-laureates", "american-biochemists", "foreign-members-of-the-royal-society", "howard-hughes-medical-investigators", "jewish-american-scientists", "members-of-the-united-states-national-academy-of-sciences", "recipients-of-the-albert-lasker-award-for-basic-medical-research", "alumni-of-the-university-of-edinburgh", "stanford-university-alumni", "university-of-california,-berkeley-college-of-letters-and-science-faculty", "university-of-california,-los-angeles-alumni", "massry-prize-recipients", "open-access-activists", "proceedings-of-the-national-academy-of-sciences-of-the-united-states-of-america-editors", "members-of-the-national-academy-of-medicine", "members-of-the-american-philosophical-society", "annual-reviews-(publisher)-editors", "american-people-of-russian-jewish-descent", "jewish-nobel-laureates", "american-fellows-of-the-royal-society"] description: "American cell biologist" topic_path: "science/biology" source: "https://en.wikipedia.org/wiki/Randy_Schekman" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary American cell biologist ::

::data[format=table title="Infobox scientist"]

FieldValue
nameRandy Schekman
birth_nameRandy Wayne Schekman
imageRandy Shekman 01.JPG
captionSchekman in 2015
birth_date
birth_placeSaint Paul, Minnesota, U.S.
thesis_titleResolution and reconstruction of a multienzyme DNA replication reaction
thesis_urlhttps://www.proquest.com/docview/302775556
thesis_year1975
work_institutionsUniversity of California, Berkeley
UCLA
Howard Hughes Medical Institute
Stanford University
alma_materUniversity of California, Los Angeles (BA)
Stanford University (PhD)
doctoral_advisorArthur Kornberg
doctoral_studentsDavid Julius
David Baker
known_forEditor-in-chief of PNAS and eLife
prizes{{Plainlist
* ForMemRS <ref name"formemrs"
* Nobel Prize in
Physiology or Medicine <ref name		"nobel-profile"{{Cite journal
last1Wickner
doi10.1073/pnas.1319309110
titleProfile of Thomas Sudhof, James Rothman, and Randy Schekman, 2013 Nobel Laureates in Physiology or Medicine
journalProceedings of the National Academy of Sciences
year2013
pmid24158482
pmc3832004
issue46
pages18349–50
bibcode2013PNAS..11018349W
doi-accessfree
website

| ::

| name = Randy Schekman | birth_name = Randy Wayne Schekman | image = Randy Shekman 01.JPG | image_size = | caption = Schekman in 2015 | birth_date = | birth_place = Saint Paul, Minnesota, U.S. | death_date = | death_place = | field = | thesis_title = Resolution and reconstruction of a multienzyme DNA replication reaction | thesis_url = https://www.proquest.com/docview/302775556 | thesis_year = 1975 | work_institutions = University of California, Berkeley UCLA Howard Hughes Medical Institute Stanford University | alma_mater = University of California, Los Angeles (BA) Stanford University (PhD) | doctoral_advisor = Arthur Kornberg | doctoral_students = David Julius David Baker | known_for = Editor-in-chief of PNAS and eLife | prizes = {{Plainlist|

Randy Wayne Schekman (born December 30, 1948) is an American cell biologist at the University of California, Berkeley, former editor-in-chief of Proceedings of the National Academy of Sciences and former editor of Annual Review of Cell and Developmental Biology.{{Cite journal | last1 = Zagorski | first1 = N. | title = Profile of Randy Schekman: Reflections on his first year as PNAS Editor-in-Chief | doi = 10.1073/pnas.0610781105 | journal = Proceedings of the National Academy of Sciences | volume = 105 | issue = 8 | pages = 2763–2765 | year = 2008 | pmid = 18287009 | pmc =2268533 | bibcode = 2008PNAS..105.2763Z | doi-access = free | last1 = Bucci | first1 = M. | title = Randy Schekman | doi = 10.1038/nchembio1106-568 | journal = Nature Chemical Biology | volume = 2 | issue = 11 | pages = 568 | year = 2006 | pmid = 17051227 | s2cid = 40321085 | doi-access = free | last1 = Zagorski | first1 = N. | title = QnAs with Randy Schekman | doi = 10.1073/pnas.0609700103 | journal = Proceedings of the National Academy of Sciences | volume = 103 | issue = 50 | pages = 18881 | year = 2006 | pmid = 17148596 | pmc =1748144 | bibcode = 2006PNAS..10318881Z | doi-access = free

Early life and education

Schekman was born in Saint Paul, Minnesota, to Alfred Schekman, an electrical engineer and computer software designer and Esther (Bader) Schekman. His family were Jewish emigrants from Russia and Bessarabia. In the late 1950s his family moved to the new suburban community of Rossmoor, located in Orange County next to Long Beach.

He graduated from Western High School in Anaheim, California, in 1966. He received a BA in molecular biology from the University of California, Los Angeles (UCLA), in 1971. He spent his third year at the University of Edinburgh in Scotland, as an exchange student. He received a PhD in 1975 from Stanford University for research on DNA replication, working with Arthur Kornberg. After joining the faculty at University of California Berkeley, he was promoted to associate professor in 1981, and professor in 1984.

Research and career

Since 1991, Schekman has been a Howard Hughes Medical Institute Investigator, Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, at the University of California, Berkeley. The Schekman Lab at that university carries out research into molecular descriptions of the process of membrane assembly and vesicular traffic in eukaryotic cells including yeast. Before that, he was a faculty member with the now disbanded Department of Biochemistry at the same university.

Awards and honors

In 1987 Schekman received the Eli Lilly Award in Microbiology. In 1992, he was elected a Member of the National Academy of Sciences. In 2002, Schekman received the Albert Lasker Award for Basic Medical Research{{Cite journal | last1 = Malhotra | first1 = V. | last2 = Emr | first2 = S. D. | title = Rothman and Schekman SNAREd by Lasker for trafficking | journal = Cell | volume = 111 | issue = 1 | pages = 1–3 | year = 2002 | pmid = 12372293 | doi=10.1016/S0092-8674(02)01008-5 | s2cid = 16018931 | doi-access = free

Schekman was elected a Foreign Member of the Royal Society (ForMemRS) in 2013. His nomination reads:

::quote

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Schekman, Thomas C. Südhof, and James Rothman were awarded the 2013 Nobel Prize for Physiology or Medicine "for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells". Schekman donated his share of the prize money, $400,000, to create an endowment for the Esther and Wendy Schekman Chair in Basic Cancer Biology at UC Berkeley. Schekman's mother and sister, for whom the post is named, both died of cancer.

In 2017, Schekman received the Golden Plate Award of the American Academy of Achievement.

In 2021, Schekman was elected honorary member of the Academy of Sciences of Moldova, with which he has been collaborating since 2019.

In 2023, he was awarded the title of Doctor Honoris Causa at Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova.

Open-access science

In December 2013, Schekman called for academic journal publishing reform and open access science publication by announcing that his lab at the University of California, Berkeley would no longer submit to the prestigious closed-access journals Nature, Cell, and Science, citing their self-serving and deleterious effects on science. He has criticized these journals for artificially restricting the number of publications accepted to drive up demand. In addition, Schekman says the journals accept papers that will be cited often, increasing the prestige of the journal, rather than those which demonstrate important results. He has said the prestige and difficulty of publishing in these journals sometimes cause scientists to cut corners or pursue trends, rather than conduct research on important questions. Schekman is the former editor of eLife, an open access journal and competitor to Nature, Cell, and Science. Papers are accepted into eLife based on review by working scientists. Access to accepted papers is free.

Parkinson's disease

In the fall of 2017, Schekman's wife, Nancy Walls, died after a 20-year struggle with Parkinson's disease. Near the end of this period, Schekman was enlisted to serve as the scientific director of a new effort called ASAP, aimed at organizing an international program of collaborative research on the origins and mechanisms of progression of Parkinson's disease. In cooperation with The Michael J. Fox Foundation and major philanthropic support, ASAP had grown by 2022 to involve 35 teams across 165 laboratories around the world. The goal of ASAP is bridge the talents of hundreds of scientists to develop novel insights leading to more effective treatments of this disease.

References

References

  1. "Julius Lab – David Julius". Physio.ucsf.edu.
  2. (2013). "Reforming research assessment". eLife.
  3. "Professor Randy Schekman ForMemRS". Royalsociety.org.
  4. "Randy Schekman: Howard Hughes Investigator and Professor of Cell and Developmental Biology".
  5. (1999). "Preface by Randy Schekman". Annual Review of Cell and Developmental Biology.
  6. "New journal editor named as Randy Schekman | Wellcome Trust".
  7. {{AcademicSearch. 2637373
  8. {{Scopus
  9. (October 8, 2013). "'Not a prank': St. Paul native lands 2013 Nobel Prize in Medicine".
  10. "The Nobel Prize in Physiology or Medicine 2013".
  11. Marroquin, Art. (October 19, 2013). "Nobel Prize winner credits high school teacher". [[Orange County Register]].
  12. "Randy Schekman, molecular biologist and UCLA alumnus, wins 2013 Nobel Prize". University of California, Los Angeles.
  13. Schekman, Randy Wayne. (1975). "Resolution and Reconstruction of a multienzyme DNA replication reaction (1975)". Stanford University.
  14. "HHMI Scientist Abstract: Randy W. Schekman, Ph.D.".
  15. (1996). "Coat Proteins and Vesicle Budding". Science.
  16. "Randy Schekman publications in Google Scholar".
  17. (1988). "A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides". Nature.
  18. (1980). "Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway". Cell.
  19. "Randy W. Schekman".
  20. "Louisa Gross Horwitz Prize Awardees".
  21. "APS Member History".
  22. "The Nobel Prize in Physiology or Medicine 2013". Nobel Foundation.
  23. (November 8, 2013). "US biologist Randy Schekman on being a Nobel Prize winner". Financial Times.
  24. "Golden Plate Awardees of the American Academy of Achievement". [[American Academy of Achievement]].
  25. MoldovaLive. (September 19, 2023). "Nobel Laureate Randy Schekman Visits Moldova, Celebrates its Roots, and Academic Collaboration".
  26. "Professor Randy Schekman, Nobel Prize Laureate in Medicine, has become Doctor Honoris Causa of "Nicolae Testemitanu" State University of Medicine and Pharmacy".
  27. "PHOTO USMF".
  28. Sample, Ian. (December 9, 2013). "Nobel winner declares boycott of top science journals". theguardian.com.
  29. [https://parkinsonsroadmap.org/# ASAP]

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