Pirolate

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Chemical compound

title: "Pirolate" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["h1-receptor-antagonists", "nitrogen-heterocycles", "lactams", "phenol-ethers", "carboxylate-esters", "heterocyclic-compounds-with-3-rings"] description: "Chemical compound" topic_path: "general/h1-receptor-antagonists" source: "https://en.wikipedia.org/wiki/Pirolate" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Chemical compound ::

| IUPAC_name = ethyl 7,8-dimethoxy-4-oxo-1,4-dihydropyrimido[4,5-b]quinoline-2-carboxylate | image = Pirolate.svg | image_class = skin-invert-image

| tradename = | pregnancy_category = | legal_status = ? | routes_of_administration = Oral

| bioavailability = | metabolism = | elimination_half-life = | excretion =

| C=16 | H=15 | N=3 | O=5 | smiles = O=C(OCC)C/1=N/C(=O)c2cc3cc(OC)c(OC)cc3nc2N\1

Pirolate (CP-32,387) is an antihistamine drug with a tricyclic chemical structure which was patented as an "antiallergen". It was never marketed and there are very few references to it in the literature.

References

(1996). "Dictionary of Pharmacological Agents". Chapman & Hall/CRC.
(1980). "Drugs affecting the respiratory system: based on a symposium sponsored by the Division of Medicinal Chemistry, at the 175th meeting of the American Chemical Society, Anaheim, California, March 13-16, 1978". The Society.

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