MDMAT

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Entactogen drug

title: "MDMAT" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["2-aminotetralins", "entactogens", "designer-drugs", "methylenedioxyphenethylamines", "serotonin-releasing-agents"] description: "Entactogen drug" topic_path: "general/2-aminotetralins" source: "https://en.wikipedia.org/wiki/MDMAT" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Entactogen drug ::

| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451557430 | image = MDMAT-structure.png | image_class = skin-invert-image | width = 250px

| tradename = | routes_of_administration = | class = Serotonin releasing agent; Entactogen | ATC_prefix = None

| legal_US = Uncontrolled; | legal_US_comment = May fall under the Federal Analogue Act | legal_status =

| CAS_number_Ref = | CAS_number = 34620-52-5 | UNII_Ref = | UNII = JV4FSP6YL3 | PubChem = 23324601 | ChemSpiderID_Ref = | ChemSpiderID = 14921388 | synonyms = 6,7-MDMAT; 6,7-Methylenedioxy-N-methyl-2-aminotetralin

| IUPAC_name = N-Methyl-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxol-6-amine | C = 12 | H = 15 | N = 1 | O = 2 | SMILES = C3c1cc2OCOc2cc1CCC3NC | StdInChI_Ref = | StdInChI = 1S/C12H15NO2/c1-13-10-3-2-8-5-11-12(15-7-14-11)6-9(8)4-10/h5-6,10,13H,2-4,7H2,1H3 | StdInChIKey_Ref = | StdInChIKey = MTRLJTZQUZHTJI-UHFFFAOYSA-N

MDMAT, also known as 6,7-methylenedioxy-N-methyl-2-aminotetralin, is a serotonin releasing agent (SRA) and possible entactogen of the 2-aminotetralin family. It is the N-methylated derivative of MDAT, similarly to the relationship of MDMA to MDA. It has been theorized to have less long-term neurotoxicity and less hallucinogenic effects than other MDxx derivatives, but no formal scientific research has been conducted specifically on MDMAT.

References

References

  1. "Controlled Substances - Alphabetical Order -". US Drug Enforcement Agency.
  2. (1971). "Potential psychotropic compounds. VIII. Synthesis and pharmacological activity of 2-aminotetralins related to psychomimetics". Chimica Therapeutica.
  3. (January 1996). "1,2,3,4-Tetrahydroisoquinoline and related analogs of the phenylalkylamine designer drug MDMA.". Medicinal Chemistry Research.
  4. (February 1990). "Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry.

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2-aminotetralinsentactogensdesigner-drugsmethylenedioxyphenethylaminesserotonin-releasing-agents