Hyperoside

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title: "Hyperoside" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["quercetin-glycosides", "flavonoid-galactosides", "kappa-opioid-receptor-antagonists", "mu-opioid-receptor-antagonists", "chemicals-in-hypericum"] topic_path: "general/quercetin-glycosides" source: "https://en.wikipedia.org/wiki/Hyperoside" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451447904 | Name = Hyperoside | ImageFile = Hyperoside.svg | ImageSize = 250px | ImageName = | IUPACName = 3-(β-D-Galactopyranosyloxy)-3′,4′,5,7-tetrahydroxyflavone | SystematicName = 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-1-benzopyran-4-one | OtherNames= Hyperozide Hyperasid Hyperosid Hyperin quercetin galactoside Quercetin-3-galactoside Quercetin-3-O-galactoside |Section1={{Chembox Identifiers | CASNo_Ref = | CASNo = 482-36-0 | ChEBI_Ref = | ChEBI = 67486 | ChEMBL = 251254 | ChemSpiderID_Ref = | ChemSpiderID = 4444962 | DrugBank = DB16403 | EC_number = 207-580-6 | KEGG_Ref = | KEGG = C10073 | PubChem = 5281643 | UNII_Ref = | UNII = 8O1CR18L82 | SMILES = c1cc(c(cc1c2c(c(=O)c3c(cc(cc3o2)O)O)O[C@H]4C@@HO)O)O | InChI = 1/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1 | InChIKey = OVSQVDMCBVZWGM-DTGCRPNFBG | StdInChI_Ref = | StdInChI = 1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1 | StdInChIKey_Ref = | StdInChIKey = OVSQVDMCBVZWGM-DTGCRPNFSA-N |Section2={{Chembox Properties | C=21 | H=20 | O=12 | Density = 1.879 g/mL | MeltingPt = | BoilingPt =

Hyperoside is a chemical compound. It is the 3-O-galactoside of quercetin.

Natural occurrences

Hyperoside has been isolated from Drosera rotundifolia, from the Lamiaceae Stachys sp. and Prunella vulgaris, from Rumex acetosella, Cuscuta chinensis seeds, from St John's wort and from Camptotheca acuminata. It is one of the phenolic compounds in the invasive plant Carpobrotus edulis and contributes to the antibacterial properties of the plant.

In Rheum nobile and R. rhaponticum, it serves as a UV blocker found in the bracts.

It is also found in Geranium niveum and Taxillus kaempferi.

References

(2005). "Antifungal Activity of Camptothecin, Trifolin, and Hyperoside Isolated from Camptotheca acuminata". Journal of Agricultural and Food Chemistry.
(2001). "Purification and identification of active antibacterial components in Carpobrotus edulis L". Journal of Ethnopharmacology.
(1999). "Geranins a and B, new antiprotozoal A-type proanthocyanidins from Geranium niveum". Journal of Natural Products.
The constituents of Taxillus kaempferi and the host, Pinus thunbergii. I. Catechins and flavones of Taxillus kaempferi. Konishi T, Nishio T, Kiyosawa S, Fujiwara Y and Konoshima T, Yakugaku Zasshi., February 1996, volume 116, issue 2, pages 148-157 (article in Japanese)

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