CBX1

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Protein-coding gene in humans

title: "CBX1" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["transcription-factors", "genes-mutated-in-mice"] description: "Protein-coding gene in humans" topic_path: "arts/film" source: "https://en.wikipedia.org/wiki/CBX1" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Protein-coding gene in humans ::

Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene.

Function

The protein is localized at heterochromatin sites, where it mediates gene silencing.

Interactions

CBX1 has been shown to interact with:

References

References

  1. (Jun 1997). "Heterochromatin protein HP1Hsbeta (p25beta) and its localization with centromeres in mitosis". Chromosoma.
  2. "Entrez Gene: CBX1 chromobox homolog 1 (HP1 beta homolog Drosophila )".
  3. (Nov 2003). "EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer". Cell.
  4. (Apr 2001). "Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins". Molecular Cell.
  5. (Apr 1999). "Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31". The EMBO Journal.

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transcription-factorsgenes-mutated-in-mice