From Surf Wiki (app.surf) — the open knowledge base

Osler's node

Painful raised skin lesions of the hands and feet

Field	Value
image	Osler Nodules Hand.jpg
caption	Osler's lesions found on the hand and fingers of a 43-year-old male with subacute bacterial endocarditis
specialty
differential	infective endocarditis

Osler's nodes are painful, red, raised lesions found typically on the hands and feet. They are associated with a number of conditions, including infective endocarditis, and are caused by immune complex deposition. Their presence is one definition of Osler's sign. TOC

Causes

Osler's nodes result from the deposition of immune complexes. The resulting inflammatory response leads to swelling, redness, and pain that characterize these lesions.

The nodes are commonly indicative of subacute bacterial endocarditis. 10–25% of endocarditis patients will have Osler's nodes.{{cite web |url=https://www.lecturio.com/concepts/endocarditis/| title=Endocarditis

Osler's nodes can also be seen in

Systemic lupus erythematosus
Marantic endocarditis
Disseminated gonococcal infection
Distal to infected arterial catheter

Etymology

Osler's nodes are named after Sir William Osler who described them in the early twentieth century. He described them as "ephemeral spots of a painful nodular erythema, chiefly in the skin of the hands and feet."

References

(2022). "Osler Node and Janeway Lesions". StatPearls Publishing.
{{DorlandsDict. seven/000097190. Osler sign
(August 1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest.
{{DorlandsDict. six/000072701. Osler nodes
{{WhoNamedIt. synd. 1702
Osler, W. (1908–1909). "Chronic infectious endocarditis". Oxford.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

symptoms-and-signs:-cardiac william-osler

Want to explore this topic further?

Ask Mako anything about Osler's node — get instant answers, deeper analysis, and related topics.

Research with Mako

Free with your Surf account

Content sourced from Wikipedia, available under CC BY-SA 4.0.

This content may have been generated or modified by AI. CloudSurf Software LLC is not responsible for the accuracy, completeness, or reliability of AI-generated content. Always verify important information from primary sources.

Report