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Krukenberg's spindle

Field	Value
image	Cornea showing Krukenberg's Spindle.jpg
caption	Slit lamp photograph showing Krukenberg's Spindle as pigment cell deposits on the cornea
field	Ophthalmology

Krukenberg's spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells that are shed during the mechanical rubbing of posterior pigment layer of the iris with the zonules that are deposited as a result of the currents of the aqueous humor. The sign was described in 1899 by Friedrich Ernst Krukenberg (1871-1946), who was a German pathologist specialising in ophthalmology.

Diagnosis

Differential diagnosis

Iritis

Painful red eye with photophobia associated with inflammation

Vortex keratopathy

Corneal deposits also known as cornea verticillata, caused by netarsudil eye drops or chronic amiodarone use for cardiac arrhythmias.

Corneal guttata

Non-transparent collagen deposits appearing following loss of corneal endothelial cells

References

Krukenberg F. (1899) Beiderseitige angeborene Melanose der Hornhaut. Klin Mbl Augenheilkd 37:254-258.
Chew, E. (June 1982). "Amiodarone-induced cornea verticillata.". Canadian Journal of Ophthalmology.
(January 2000). "Corneal guttata associated with the corneal dystrophy resulting from a betaig-h3 R124H mutation". The British Journal of Ophthalmology.

Info: Wikipedia Source

This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page.

medical-signs eye-diseases

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