Α-Cadinol

Natural occurrence

This compound is found in essential oils and extracts of many plants, such as

• Agrotaxis selaginoides,
• Tabernaemontana catharinensis
• Litsea acutivena (7.7%),
• Salvia aratocensis (20%),
• Protium giganteum (7%),
• Uvaria ovata root bark (13–24%),
• Plinia trunciflora (19%)
• Tanacetum sonbolii (35%)
• Schisandra chinensis berries (5%),
• Melia azedarach (11%),
• Neolitsea parvigemma (10%),
• Tetradenia riparia (8%)

Biological activity

α-Cadinol was said to act as anti-fungal and was proposed as a possible remedy for drug-resistant tuberculosis.

References

References

1. (1981). "Configurations and conformations of torreyol (δ-cadinol), α-cadinol, T-muurolol and T-cadinol". Tetrahedron.
2. (1958). "The chemistry of cadinenes and cadinols". Tetrahedron.
3. (2012). "Chemical composition and antioxidant activity of the essential oil of ''Tabernaemontana catharinensis'' A. DC. Leaves". Natural Product Research.
4. (2011). "Composition and antimicrobial activity of the leaf and twig oils of ''Litsea acutivena'' from Taiwan". Natural Product Communications.
5. (2011). "Composition of three essential oils, and their mammalian cell toxicity and antimycobacterial activity against drug resistant-tuberculosis and nontuberculous mycobacteria strains". Natural Product Communications.
6. (2011). "Volatile constituents of two species of ''Protium'' from the Atlantic rainforest in the state of Pernambuco, Brazil". Natural Product Communications.
7. (2011). "Essential oil of three ''Uvaria'' species from Ivory Coast". Natural Product Communications.
8. (2011). "Chemical and biological evaluation of essential oils from two species of Myrtaceae - ''Eugenia uniflora'' L. And ''Plinia trunciflora'' (O. Berg) Kausel". Molecules (Basel, Switzerland).
9. (2011). "Essential oil composition and antioxidant activities of the various extracts of ''Tanacetum sonbolii'' Mozaff. (Asteraceae) from Iran". Natural Product Research.
10. (2011). "Chemical composition and antioxidant activity of essential oil from berries of ''Schisandra chinensis'' (Turcz.) Baill". Natural Product Research.
11. (2011). "Comparison of headspace solid-phase microextraction with conventional extraction for the analysis of the volatile components in ''Melia azedarach''". Talanta.
12. (2011). "Composition and antifungal activities of the leaf essential oil of ''Neolitsea parvigemma'' from Taiwan". Natural Product Communications.
13. (2010). "Seasonal variation, chemical composition, and analgesic and antimicrobial activities of the essential oil from leaves of ''Tetradenia riparia'' (Hochst.) Codd in southern Brazil". Molecules.
14. (2011). "Bioactive phytochemicals of leaf essential oils of ''Cinnamomum osmophloeum'' prevent lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced acute hepatitis in mice". J. Agric. Food Chem..