Uterine adenosarcoma
title: "Uterine adenosarcoma" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["gynaecological-cancer"] topic_path: "philosophy" source: "https://en.wikipedia.org/wiki/Uterine_adenosarcoma" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0
::data[format=table title="Infobox medical condition (new)"]
| Field | Value |
|---|---|
| name | Uterine adenosarcoma |
| synonyms | Adenosarcoma of the uterus, Müllerian adenosarcoma of the uterus |
| image | Uterine adenosarcoma - high mag.jpg |
| caption | Micrograph of a uterine adenosarcoma showing a mitotically active malignant stroma and benign glands. H&E stain. |
| field | Gynecology |
| :: |
| name = Uterine adenosarcoma | synonyms = Adenosarcoma of the uterus, Müllerian adenosarcoma of the uterus | image = Uterine adenosarcoma - high mag.jpg | caption = Micrograph of a uterine adenosarcoma showing a mitotically active malignant stroma and benign glands. H&E stain. | pronounce = | field = Gynecology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = Uterine adenosarcoma is an uncommon form of cancer that arises from mesenchymal tissue of the uterus and has a benign glandular component.
Signs and symptoms
The most common presentation is vaginal bleeding. Other presentations include pelvic mass and uterine polyp. Generally, the clinical findings are non-specific.
Pathology
Uterine adenosarcoma have, by definition, a malignant stroma and benign glandular elements. The World Health Organization (WHO) criteria have a mitotic rate cut point; however, this is often disregarded, as bland-appearing tumours with a low mitotic rate are known to metastasize occasionally.
Image: Uterine adenosarcoma - low mag.jpg | Low mag. Image: Uterine adenosarcoma - add - intermed mag.jpg | Intermed. mag. Image: Uterine adenosarcoma - very high mag.jpg | Very high mag.
Treatment
Uterine adenosarcomas are typically treated with a total abdominal hysterectomy and bilateral salpingoophorectomy (TAH-BSO). Ovary-sparing surgery may be done in women wishing to preserve fertility.
Prognosis
The prognosis is determined primarily by the cancer stage. Most tumours are discovered at an early stage and have a good prognosis, especially when compared to uterine carcinosarcoma. Five-year survival for stage I and stage III tumours is approximately 80% and 50% respectively.
References
References
- (1998). "Clinicopathologic analysis of mullerian adenosarcoma: the M.D. Anderson Cancer Center experience.". Oncol Rep.
- (Mar 2010). "Mullerian adenosarcoma of the female genital tract.". Adv Anat Pathol.
- (2010). "Mullerian adenosarcoma of the uterus: a rare neoplasm with a need for onco-fertility.". Eur J Gynaecol Oncol.
- (Nov 2010). "Long-term outcome and natural history of uterine adenosarcomas.". Gynecol Oncol.
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