Uri Alon

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Israeli biologist and academic

title: "Uri Alon" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["1969-births", "living-people", "members-of-the-european-molecular-biology-organization", "academic-staff-of-weizmann-institute-of-science", "overton-prize-winners", "israeli-bioinformaticians", "systems-biologists", "hebrew-university-of-jerusalem-alumni", "israeli-people-of-romanian-jewish-descent", "israeli-physicists", "network-scientists", "talpiot-program-alumni", "scientists-from-tel-aviv", "jewish-biologists", "weizmann-institute-of-science-alumni"] description: "Israeli biologist and academic" topic_path: "science/biology" source: "https://en.wikipedia.org/wiki/Uri_Alon" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Israeli biologist and academic ::

::data[format=table title="Infobox scientist"]

FieldValue
nameUri Alon
native_nameאורי אלון
native_name_langhe
imageAlon Uri.jpg
image_size225px
captionUri Alon
birth_date
death_date
workplacesWeizmann Institute of Science
Princeton University
alma_materHebrew University of Jerusalem
Weizmann Institute of Science
doctoral_advisorDavid Mukamel
academic_advisors{{Plainlist
* Stanislas Leibler<ref name"overton"}}
doctoral_studentsRon Milo
known_forNetwork motifs
awardsOverton Prize (2004)
signature
website
::

| name = Uri Alon | native_name = אורי אלון | native_name_lang = he | image = Alon Uri.jpg | image_size = 225px | alt = | caption = Uri Alon | birth_date = | birth_place = | death_date = | death_place = | residence = | citizenship = | nationality = | fields = | workplaces = Weizmann Institute of Science Princeton University | alma_mater = Hebrew University of Jerusalem Weizmann Institute of Science | doctoral_advisor = David Mukamel | academic_advisors = {{Plainlist|

  • Dov Shvarts
  • Stanislas Leibler}} | doctoral_students = Ron Milo | notable_students = | known_for = Network motifs | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = Overton Prize (2004) | signature = | signature_alt = | footnotes = | spouse = | website =

Uri Alon (; born 1969) is a Professor and Systems Biologist at the Weizmann Institute of Science. His highly cited research investigates gene expression, network motifs and the design principles of biological networks in Escherichia coli and other organisms using both computational biology and traditional experimental wet laboratory techniques.

Education

Alon earned his bachelor's and master's degrees from the Hebrew University of Jerusalem and his Ph.D. in Theoretical Physics from the Weizmann Institute of Science.

Career

After having his interest in biology sparked, Alon headed to Princeton University for his postdoctoral work in experimental biology. He returned to the Weizmann Institute as a professor.

Alon features in several popular videos on YouTube such as Sunday at the Lab (with Michael Elowitz) and How to Give a Good Talk. As of 2011, he is the author of the most highly bookmarked scientific paper on CiteULike How To Choose a Good Scientific Problem and How to Build a Motivated Research Group.

In 2021 he was appointed visiting professor in the bioengineering department of Stanford University. He is a member of the IBS Biomedical Mathematics Group.

Research

Uri Alon significantly contributed to our understanding of gene regulatory networks and generalized the term network motif in 2002.

Together with his team, he reunited different theories of endocrine feedback loops by introducing the closely related concepts of dynamical compensation and autoimmune surveillance of hypersecreting mutants (ASHM). The theories are able to explain a plethora of phenomena ranging from circannual endocrine rhythms over type 2 diabetes and other common endocrine disorders to alcohol addiction and age-related diseases.

Awards

In 2004 Alon was awarded the Overton Prize for "outstanding accomplishment by a scientist in the early to mid stage of his or her career" by the International Society for Computational Biology. Alon has also been awarded:

References

References

  1. "Wis-Find: Author Search Results". weizmann.ac.il.
  2. (1996). "Roughening Transition in a One-Dimensional Growth Process". Physical Review Letters.
  3. "ISCB Newsletter 7-3". iscb.org.
  4. "Homepage - Uri Alon". weizmann.ac.il.
  5. {{GoogleScholar. fMQZybAAAAAJ
  6. (1999). "Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays". Proceedings of the National Academy of Sciences.
  7. (2002). "Network Motifs: Simple Building Blocks of Complex Networks". Science.
  8. (2002). "Network motifs in the transcriptional regulation network of Escherichia coli". Nature Genetics.
  9. Uri Alon. (2007). "An introduction to systems biology: design principles of biological circuits". Chapman & Hall/CRC.
  10. {{AcademicSearch. 2452390
  11. "arXiv.org Search". arxiv.org.
  12. ""Uri Alon's Song - Sunday at the Lab co-written with Elowitz"".
  13. ""How to Give a Good Talk by Uri Alon"".
  14. "CiteULike CiteGeist: Popular Papers".
  15. (2009). "How to Choose a Good Scientific Problem". Molecular Cell.
  16. (2010). "How to Build a Motivated Research Group". Molecular Cell.
  17. "Uri Alon".
  18. R. Milo, S. Shen-Orr, S. Itzkovitz, N. Kashtan, D. Chklovskii, U. Alon: ''Network motifs: simple building blocks of complex networks'', Science 298, 2002, S. 824–827
  19. S. Shen-Orr, R. Milo, S. Mangan, U. Alon: ''Network motifs in the transcriptional regulation network of Escherichia coli'', Nature Genetics 31, 2002,: 64–68
  20. (June 2007). "Network motifs: theory and experimental approaches". Nature Reviews Genetics.
  21. (8 November 2016). "Dynamical compensation in physiological circuits.". Molecular Systems Biology.
  22. (26 August 2020). "Timescales of Human Hair Cortisol Dynamics.". iScience.
  23. (19 May 2020). "Endocrine Autoimmune Disease as a Fragility of Immune Surveillance against Hypersecreting Mutants.". Immunity.
  24. (16 February 2021). "Hormone seasonality in medical records suggests circannual endocrine circuits.". Proceedings of the National Academy of Sciences of the United States of America.
  25. (26 June 2017). "Biphasic response as a mechanism against mutant takeover in tissue homeostasis circuits.". Molecular Systems Biology.
  26. (July 2020). "A new model for the HPA axis explains dysregulation of stress hormones on the timescale of weeks.". Molecular Systems Biology.
  27. (19 March 2021). "An opponent process for alcohol addiction based on changes in endocrine gland mass.". iScience.
  28. (March 2021). "Senescent cells and the incidence of age-related diseases.". Aging Cell.
  29. "Uri Alon". f1000.com.
  30. "Radcliffe Fellows".
  31. "2014 HFSP Nakasone Award goes to Uri Alon". hfsp.org.

::callout[type=info title="Wikipedia Source"] This article was imported from Wikipedia and is available under the Creative Commons Attribution-ShareAlike 4.0 License. Content has been adapted to SurfDoc format. Original contributors can be found on the article history page. ::

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