Transfluthrin

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Volatile pyrethroid insecticide used indoor against insects such as moths or mosquitoes

title: "Transfluthrin" type: doc version: 1 created: 2026-02-28 author: "Wikipedia contributors" status: active scope: public tags: ["(2,3,5,6-tetrafluorophenyl)methyl-3-ethenyl-2,2-dimethylcyclopropane-1-carboxylate-derivatives", "organochlorides"] description: "Volatile pyrethroid insecticide used indoor against insects such as moths or mosquitoes" topic_path: "general/2-3-5-6-tetrafluorophenyl-methyl-3-ethenyl-2-2-dimethylcyclopropane-1-carboxylate-derivatives" source: "https://en.wikipedia.org/wiki/Transfluthrin" license: "CC BY-SA 4.0" wikipedia_page_id: 0 wikipedia_revision_id: 0

::summary Volatile pyrethroid insecticide used indoor against insects such as moths or mosquitoes ::

| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 470612439 | ImageFile = Transfluthrin-2D-skeletal.png | ImageSize = | PIN = (2,3,5,6-Tetrafluorophenyl)methyl (1R,3S)-3-(2,2-dichloroethen-1-yl)-2,2-dimethylcyclopropane-1-carboxylate | OtherNames = – CA: (1R-trans)-(2,3,5,6-tetrafluorophenyl)methyl 3-(2,2-dichloroethenyl)-2,2- dimethylcyclopropanecarboxylate – Common name transfluthrin: E-ISO (published). – Synonym: benfluthrin (Bayer), NAK 4455 |Section1={{Chembox Identifiers | ChemSpiderID_Ref = | ChemSpiderID = 570973 | InChI = 1/C15H12Cl2F4O2/c1-15(2)7(3-10(16)17)11(15)14(22)23-5-6-12(20)8(18)4-9(19)13(6)21/h3-4,7,11H,5H2,1-2H3/t7-,11+/m1/s1 | InChIKey = DDVNRFNDOPPVQJ-HQJQHLMTBF | StdInChI_Ref = | StdInChI = 1S/C15H12Cl2F4O2/c1-15(2)7(3-10(16)17)11(15)14(22)23-5-6-12(20)8(18)4-9(19)13(6)21/h3-4,7,11H,5H2,1-2H3/t7-,11+/m1/s1 | StdInChIKey_Ref = | StdInChIKey = DDVNRFNDOPPVQJ-HQJQHLMTSA-N | CASNo_Ref = | CASNo =118712-89-3 | UNII_Ref = | UNII = QWL3SKA6EG | PubChem = 656612 | KEGG_Ref = | KEGG = C13410 | ChEBI_Ref = | ChEBI = 32253 | SMILES = Cl/C(Cl)=C/[C@@H]2C@@HC2(C)C |Section2={{Chembox Properties | C=15 | H=12 | Cl=2 | F=4 | O=2 | Appearance = Colorless crystals | Density = 1.507 g/cm3 (23 °C) | MeltingPtC = 32 | BoilingPtC = 135 | BoilingPt_notes = at 0.1 mm Hg ~ 250 °C at 760 mm Hg | VaporPressure = Conflicting data: 1×10−4 Pa (20 °C; 15 μg/m3) or 9×10−4 Pa (20 °C) | Solubility = 5.7×10−5 g/L = 57 μg/L | SolubleOther = very soluble | Solvent = hexane, isopropanol, toluene, dichloromethane |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt =

Transfluthrin is a fast-acting pyrethroid insecticide with low persistency. It has the molecular formula C15H12Cl2F4O2.

Transfluthrin can be used in the indoor environment against flies, mosquitoes, moths and cockroaches. It is a relatively volatile substance and acts as a contact and inhalation agent.

Transfluthrin, if used contrary to product instructions, may cause symptoms of poisoning including nervousness, anxiety, tremor, convulsions, skin allergies, sneezing, running nose and irritation. Treatment depends on symptoms. No specific antidotes are known, but antihistamines may help to control any allergies.

In experiments, transfluthrin was shown to kill 85 percent of mosquitos within one hour of exposure at concentrations below 0.3 μg/m3 (which was the detection limit) in air. (The data suggests that transfluthrin is effective at these concentrations within much less than an hour of exposure.)

Various household transfluthrin products such as vaporizers and mosquito coils may result in concentrations of 15 μg/m3 to 40 μg/m3. In the EU, the acceptable exposure level (AEL) for humans is 500 μg/m3.

References

References

  1. [http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/1282.htm Pesticides properties database]. K Lewis et al., DOI: 10.1080/10807039.2015.1133242
  2. (November 2006). "WHO Specifications and evaluations for public health pesticides: Transfluthrin. WHO specification 741/2006 – Evaluation Report 741/2002 (November 2006)". World Health Organization (WHO).
  3. (September 2002). "Personal protection against mosquitoes in Dar es Salaam, Tanzania, by using a kerosene oil lamp to vaporize transfluthrin: Mosquito repellent vaporizing lamps". Medical and Veterinary Entomology.
  4. Information on the leaflet supplied with the product: Good Knight Advanced (ACTIV+ System) Mosquito Repellent Vaporizer cartridge (UPC Code:8 901157 001143)
  5. N.J. Martin et al., [https://doi.org/10.1186/s12936-019-3092-4 The impact of transfluthrin on the spatial repellency of the primary malaria mosquito vectors in Vietnam: Anopheles dirus and Anopheles minimus.]. Malar J 19, 9 (2020)
  6. [http://dissemination.echa.europa.eu/Biocides/ActiveSubstances/1404-18/1404-18_Assessment_Report.pdf Assessment report: Transfluthrin] for EU regulation No. 528/2012 (2014)

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(2,3,5,6-tetrafluorophenyl)methyl-3-ethenyl-2,2-dimethylcyclopropane-1-carboxylate-derivativesorganochlorides